Takeda Takamori, Ikeda Takuo, Tsutsumi Takeshi
a Department of Otolaryngology , Tokyo Medical and Dental University , Tokyo , Japan.
b Department of Otolaryngology , Tsudumigaura Medical Center for Children with Disabilities , Yamaguchi , Japan.
Acta Otolaryngol. 2019 Jul;139(7):581-587. doi: 10.1080/00016489.2019.1607975. Epub 2019 May 20.
The thickness of Listing's plane accurately reflects gravitational recognition, constructed through the integration of visual, vestibular, and proprioceptive sensory input in the neural integrator of the central nervous system. Spinocerebellar degeneration (SCD) is a progressive degenerative disease mainly involving the cerebellum and brainstem that leads to destabilize the gravitational recognition, and may thicken thickening of Listing's plane. The aim of this study is to evaluate the gravitational recognition in response to positional change in patients with SCD, using the thickness of Listing's plane as a parameter. In this prospective study, we evaluated the thickness of Listing's plane in 21 consecutive patients with SCD and 32 healthy subjects in the seated and supine positions, and investigated the association with other neuro-otological examinations (electronystagmography including caloric test and posturography). We detected significant thickening of Listing's plane in SCD patients only when they were in the seated position. The thickness of Listing's plane correlated with neither the caloric response nor Romberg's ratio or the total center of the pressure path length. The thickness of Listing's plane could be a useful parameter for assessing a gravity-oriented internal model in SCD patients.
利斯廷平面的厚度准确反映了重力感知，它是通过中枢神经系统神经整合器中视觉、前庭和本体感觉输入的整合构建而成。脊髓小脑变性（SCD）是一种主要累及小脑和脑干的进行性退行性疾病，会导致重力感知不稳定，并可能使利斯廷平面增厚。本研究的目的是以利斯廷平面的厚度为参数，评估SCD患者对体位变化的重力感知。在这项前瞻性研究中，我们评估了21例连续的SCD患者和32名健康受试者在坐位和仰卧位时利斯廷平面的厚度，并研究了其与其他神经耳科检查（包括冷热试验和姿势描记法的眼震电图）的相关性。我们仅在SCD患者坐位时检测到利斯廷平面明显增厚。利斯廷平面的厚度与冷热反应、罗姆伯格比率或压力路径长度的总中心均无相关性。利斯廷平面的厚度可能是评估SCD患者重力导向内部模型的一个有用参数。
