Jarrah Mohamad I, Yassin Ahmed M, Ibdah Rasheed K, Ibnian Ali M, Eyadeh Ahmad A, Khassawneh Basheer Y
Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of Neuro sciences, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Vasc Health Risk Manag. 2019 May 1;15:109-113. doi: 10.2147/VHRM.S203307. eCollection 2019.
This study aimed to utilize a validated sleep questionnaire as a screening tool for symptoms and risk of obstructive sleep apnea in patients undergoing coronary catheterization in Jordan. A cross-sectional design was used to screen adult patients undergoing coronary catheterization for obstructive sleep apnea (OSA). The Berlin sleep questionnaire was used to record nocturnal and daytime symptoms of OSA and to stratify patients into "low-risk" or "high-risk" for OSA. Coronary artery disease was defined as ≥50% intraluminal stenosis in at least one coronary vessel. A total of 398 patients were studied, mean age was 58.7 years (SD=10.70), ranging from 21-92 years, and 68.6% were males. Based on the Berlin sleep questionnaire's definition, 176 patients (44.2%) were at high-risk for obstructive sleep apnea. Snoring was reported by 61%; loud in 42.1%, and frequent in 62%. Daytime sleepiness was reported by 36%, and 18.9% had fallen asleep while driving. Witnessed apnea during sleep was less reported (7.8%). Prevalence of symptoms and risk of OSA were not different between patients with and without coronary artery disease, >0.05. In addition, logistic regression indicated that there was no significant association between risk of OSA and coronary artery disease, adjusted (odds ratio=0.93, 95% Confidence Interval=0.60-1.44, =0.752). Symptoms and risk of obstructive sleep apnea were common among adult Jordanians undergoing coronary catheterization. There was no association between risk of obstructive sleep apnea and coronary artery disease. Larger studies are needed to assess the role of screening for obstructive sleep apnea in this patient population.
本研究旨在使用经过验证的睡眠问卷作为约旦接受冠状动脉造影术患者阻塞性睡眠呼吸暂停症状及风险的筛查工具。采用横断面设计对接受冠状动脉造影术的成年患者进行阻塞性睡眠呼吸暂停（OSA）筛查。使用柏林睡眠问卷记录OSA的夜间和白天症状，并将患者分为OSA“低风险”或“高风险”。冠状动脉疾病定义为至少一条冠状动脉管腔内狭窄≥50%。共研究了398例患者，平均年龄58.7岁（标准差=10.70），年龄范围为21 - 92岁，男性占68.6%。根据柏林睡眠问卷的定义，176例患者（44.2%）存在阻塞性睡眠呼吸暂停高风险。61%的患者报告有打鼾；其中42.1%鼾声较大，62%经常打鼾。36%的患者报告有白天嗜睡，18.9%的患者在开车时睡着过。睡眠中被目击的呼吸暂停报告较少（7.8%）。有或无冠状动脉疾病患者的症状患病率及OSA风险无差异，P>0.05。此外，逻辑回归表明，OSA风险与冠状动脉疾病之间无显著关联，校正后（比值比=0.93，95%置信区间=0.60 - 1.44，P=0.752）。阻塞性睡眠呼吸暂停的症状及风险在接受冠状动脉造影术的约旦成年患者中很常见。阻塞性睡眠呼吸暂停风险与冠状动脉疾病之间无关联。需要更大规模的研究来评估对该患者群体进行阻塞性睡眠呼吸暂停筛查的作用。
