Medical Engineering Research Group, Faculty of Science and Engineering, Anglia Ruskin University, Chelmsford, United Kingdom.
Leon Root, Motion Analysis Laboratory, Hospital for Special Surgery, New York, New York.
J Orthop Res. 2019 Oct;37(10):2149-2156. doi: 10.1002/jor.24379. Epub 2019 Jun 19.
The Atlas™ unicompartmental knee system is a second-generation extra-articular unloading implant for patients with mild to moderate medial knee osteoarthritis. The technology acts to reduce a portion of the weight-bearing load exerted on the medial knee during physical activity thereby, reducing the mechanical stress imposed on a degenerative joint. The purpose of the present study was to evaluate the effects of the Atlas™ on tibiofemoral joint mechanics during walking. A computer-aided design assembly of the Atlas™ was virtually implanted on the medial aspect of a previously validated finite element tibiofemoral joint model. Data for knee joint forces and moments from an anthropometrically matched male were applied to the model to quasi-statically simulate the stance phase of gait. Predictions of tibiofemoral joint mechanics were computed pre- and post-virtual implantation of the Atlas™. Compressive force in the medial tibiofemoral compartment was reduced by a mean of 53%, resulting in the decrement of mean cartilage-cartilage and cartilage-meniscus von Mises stress by 31% and 32%, respectively. The Atlas™ was not predicted to transfer net loading to the lateral compartment. The tibiofemoral joint model exhibited less internal-external rotation and anterior-posterior translation post-Atlas™, indicating a change in the kinematic environment of the knee. From a biomechanical perspective, extra-articular joint unloading may serve as a treatment option for patients recalcitrant to conservative care. Evaluation of mechanical changes in the tibiofemoral joint demonstrate the potential treatment mechanism of the Atlas™, in accordance with the available clinical data. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:2149-2156, 2019.
Atlas™ 单髁膝关节系统是一种第二代关节外减压植入物,适用于有轻度至中度内侧膝关节骨关节炎的患者。该技术可减轻患者在进行体育活动时内侧膝关节承受的部分负重,从而减少对退行性关节的机械压力。本研究的目的是评估 Atlas™ 在行走过程中对胫股关节力学的影响。通过计算机辅助设计,将 Atlas™ 虚拟植入到经过验证的有限元胫股关节模型的内侧。将来自与人体测量匹配的男性的膝关节力和力矩数据应用于模型,以准静态模拟步态的站立阶段。在虚拟植入 Atlas™ 之前和之后计算胫股关节力学的预测值。内侧胫股关节间隙的压缩力平均降低了 53%,导致软骨-软骨和软骨半月板 von Mises 应力分别降低了 31%和 32%。Atlas™ 未被预测会将净负荷转移到外侧关节间隙。胫股关节模型在植入 Atlas™ 后表现出较小的内外旋转和前后平移,表明膝关节运动环境发生了变化。从生物力学的角度来看,关节外关节减压可能是对保守治疗有抵抗力的患者的一种治疗选择。对胫股关节机械变化的评估表明了 Atlas™ 的潜在治疗机制,与现有临床数据一致。©2019 矫形研究协会。由 Wiley Periodicals, Inc. 出版。J 骨科研究 37:2149-2156, 2019.