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内侧膝关节减压植入物对行走时胫股关节力学的影响。

Effects of a Medial Knee Unloading Implant on Tibiofemoral Joint Mechanics During Walking.

机构信息

Medical Engineering Research Group, Faculty of Science and Engineering, Anglia Ruskin University, Chelmsford, United Kingdom.

Leon Root, Motion Analysis Laboratory, Hospital for Special Surgery, New York, New York.

出版信息

J Orthop Res. 2019 Oct;37(10):2149-2156. doi: 10.1002/jor.24379. Epub 2019 Jun 19.

Abstract

The Atlas™ unicompartmental knee system is a second-generation extra-articular unloading implant for patients with mild to moderate medial knee osteoarthritis. The technology acts to reduce a portion of the weight-bearing load exerted on the medial knee during physical activity thereby, reducing the mechanical stress imposed on a degenerative joint. The purpose of the present study was to evaluate the effects of the Atlas™ on tibiofemoral joint mechanics during walking. A computer-aided design assembly of the Atlas™ was virtually implanted on the medial aspect of a previously validated finite element tibiofemoral joint model. Data for knee joint forces and moments from an anthropometrically matched male were applied to the model to quasi-statically simulate the stance phase of gait. Predictions of tibiofemoral joint mechanics were computed pre- and post-virtual implantation of the Atlas™. Compressive force in the medial tibiofemoral compartment was reduced by a mean of 53%, resulting in the decrement of mean cartilage-cartilage and cartilage-meniscus von Mises stress by 31% and 32%, respectively. The Atlas™ was not predicted to transfer net loading to the lateral compartment. The tibiofemoral joint model exhibited less internal-external rotation and anterior-posterior translation post-Atlas™, indicating a change in the kinematic environment of the knee. From a biomechanical perspective, extra-articular joint unloading may serve as a treatment option for patients recalcitrant to conservative care. Evaluation of mechanical changes in the tibiofemoral joint demonstrate the potential treatment mechanism of the Atlas™, in accordance with the available clinical data. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:2149-2156, 2019.

摘要

Atlas™ 单髁膝关节系统是一种第二代关节外减压植入物,适用于有轻度至中度内侧膝关节骨关节炎的患者。该技术可减轻患者在进行体育活动时内侧膝关节承受的部分负重,从而减少对退行性关节的机械压力。本研究的目的是评估 Atlas™ 在行走过程中对胫股关节力学的影响。通过计算机辅助设计,将 Atlas™ 虚拟植入到经过验证的有限元胫股关节模型的内侧。将来自与人体测量匹配的男性的膝关节力和力矩数据应用于模型,以准静态模拟步态的站立阶段。在虚拟植入 Atlas™ 之前和之后计算胫股关节力学的预测值。内侧胫股关节间隙的压缩力平均降低了 53%,导致软骨-软骨和软骨半月板 von Mises 应力分别降低了 31%和 32%。Atlas™ 未被预测会将净负荷转移到外侧关节间隙。胫股关节模型在植入 Atlas™ 后表现出较小的内外旋转和前后平移,表明膝关节运动环境发生了变化。从生物力学的角度来看,关节外关节减压可能是对保守治疗有抵抗力的患者的一种治疗选择。对胫股关节机械变化的评估表明了 Atlas™ 的潜在治疗机制,与现有临床数据一致。©2019 矫形研究协会。由 Wiley Periodicals, Inc. 出版。J 骨科研究 37:2149-2156, 2019.

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