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基于阿片类药物的圈养细纹斑马固定方案比较()。

A COMPARISON OF OPIOID-BASED PROTOCOLS FOR IMMOBILIZATION OF CAPTIVE GREVY'S ZEBRA ().

作者信息

Stuchin Margot, Mama Khursheed R, Zuba Jeffrey R, Oosterhuis James E, Lamberski Nadine, Olea-Popelka Francisco

机构信息

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Harter Veterinary Medical Center, San Diego Zoo Safari Park, Escondido, CA 92027, USA.

出版信息

J Zoo Wildl Med. 2019 Mar 1;50(1):258-261. doi: 10.1638/2018-0108.

Abstract

Grevy's zebra () is an endangered species often found in zoological collections. Veterinary care for this species often requires immobilization. This study retrospectively evaluated behavioral and physiological parameters from Grevy's zebra records after three immobilization protocols: etorphine and alpha-2 agonist (EA2; = 11); etorphine, alpha-2 agonist, and ketamine (EA2K; = 16); and thiafentanil, alpha-2 agonist, and ketamine (TA2K; = 6). Median time to working depth was statistically different ( = 0.03; EA2 = 6.5 min, EA2K = 6.3 min, TA2K = 14.5 min) by the Kruskal-Wallis test. When EA2 + EA2K were combined and compared with TA2K (Wilcoxon rank sum test), median recumbency time ( = 0.02) was also significantly longer (15 min compared with 6 min) for TA2K. There were no significant differences between the groups for physiological parameters or recovery time after reversal. Although all protocols produced anesthesia in Grevy's zebra, increased time to achieve working depth was observed with the alpha-2 and thiafentanil combinations.

摘要

细纹斑马()是一种濒危物种,常在动物园中被发现。对该物种的兽医护理通常需要进行麻醉保定。本研究回顾性评估了三种麻醉保定方案后细纹斑马记录中的行为和生理参数:埃托啡与α-2激动剂(EA2; = 11);埃托啡、α-2激动剂和氯胺酮(EA2K; = 16);以及噻芬太尼、α-2激动剂和氯胺酮(TA2K; = 6)。通过Kruskal-Wallis检验,达到有效麻醉深度的中位时间在统计学上存在差异( = 0.03;EA2 = 6.5分钟,EA2K = 6.3分钟,TA2K = 14.5分钟)。当将EA2 + EA2K合并并与TA2K进行比较时(Wilcoxon秩和检验),TA2K的中位躺卧时间( = 0.02)也显著更长(15分钟对比6分钟)。各组之间在生理参数或苏醒后的恢复时间方面没有显著差异。尽管所有方案都能使细纹斑马麻醉,但α-2激动剂与噻芬太尼联合使用时,达到有效麻醉深度的时间有所增加。

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