Geriatric Dialysis Program, Toronto, ON Canada.
Geriatric Dialysis Program, Toronto, ON Canada
Perit Dial Int. 2019 Jul-Aug;39(4):375-381. doi: 10.3747/pdi.2018.00189. Epub 2019 May 23.
Home dialysis therapies, including peritoneal dialysis (PD), are preferred treatment strategies, offering flexibility and improved wellbeing. However, patients with complex disease and comorbidity may require assistance with personal care and healthcare-related tasks. The study objective was to formally assess the type and frequency of PD assistance received by patients over 50, and the relationship to observed frailty, functional status, and cognitive ability at the time of PD therapy initiation.Using a multicentered, prospective observational study design, patients aged ≥ 50 years were recruited from those starting PD. Patients underwent formal evaluation using validated components of a Comprehensive Geriatric Assessment. The receipt and nature of assistance with PD tasks were assessed 1 month after dialysis start by questionnaire.A total of 121 patients (age 69 ± 10 years, 67% male, 54% diabetic) were recruited. A total of 75 (62%) patients received assistance for a variety of tasks from friends or family ( = 41, 34%) or a paid caregiver ( = 34, 28%) 1 month after starting dialysis. At baseline, there was a high prevalence of functional dependency (79/120, 66%), frailty (71/110, 65%), and impaired cognition (68/115, 59%). Only 5% were fully independent, clinically robust, and scored within the normal range on cognitive testing. Factors associated with PD assistance included comorbidity ( < 0.03), cognitive impairment ( < 0.0001), and functional dependence ( < 0.02).Older patients initiating PD in the outpatient setting have high rates of frailty, functional dependence, and cognitive changes at the time they initiate dialysis. More research is required to better understand how those factors contribute to the use of PD assistance.
家庭透析疗法,包括腹膜透析(peritoneal dialysis,PD),是首选的治疗策略,提供了灵活性和改善的生活质量。然而,患有复杂疾病和合并症的患者可能需要个人护理和医疗相关任务的帮助。本研究的目的是正式评估 50 岁以上患者接受 PD 治疗时接受的 PD 辅助类型和频率,以及与观察到的虚弱、功能状态和认知能力的关系。
使用多中心、前瞻性观察性研究设计,从开始 PD 的患者中招募年龄≥50 岁的患者。患者接受了全面老年评估的验证成分的正式评估。在开始透析后 1 个月,通过问卷评估 PD 任务的辅助接收和性质。
共招募了 121 名患者(年龄 69±10 岁,67%为男性,54%为糖尿病患者)。共有 75 名(62%)患者在开始透析后 1 个月接受了来自朋友或家人(41 名,34%)或付费护理人员(34 名,28%)的各种任务的帮助。在基线时,有很高的功能依赖率(79/120,66%)、虚弱率(71/110,65%)和认知障碍率(68/115,59%)。只有 5%的患者完全独立,临床稳健,认知测试评分正常。与 PD 辅助相关的因素包括合并症(<0.03)、认知障碍(<0.0001)和功能依赖(<0.02)。
在门诊环境中开始 PD 的老年患者在开始透析时虚弱、功能依赖和认知变化的发生率很高。需要进一步研究以更好地了解这些因素如何影响 PD 辅助的使用。