Cassar Noel, Cortes-Cerisuelo Miriam, Bambridge Carly, Ali Amir, Heaton Nigel, Vilca-Melendez Hector
Institute of Liver Studies, King's Healthcare Partners Denmark Hill Site, London, UK.
Pediatr Transplant. 2019 Aug;23(5):e13473. doi: 10.1111/petr.13473. Epub 2019 May 24.
Primary abdominal wall closure after intestinal and multivisceral transplantation may not be possible because of loss of abdominal domain and/or graft size/abdominal cavity mismatch. Traditional closure techniques for the open abdomen may not be valid in these circumstances because of severe scarring of the abdominal wall from multiple previous surgeries in this particular group of patients. We present our initial experience with the use of non-vascularized abdominal rectus muscle fascia in two patients who underwent deceased donation and living-related combined liver and small bowel transplantation, respectively, and who could not be closed primarily. The donor fascia was attached to the recipient fascia in both patients. In either case, there was not enough skin cover for closure, the wound was left open, and a negative pressure dressing was applied. In both cases, over a period of 6 months after placement of the non-vascularized abdominal rectus muscle fascia, the wound contracted, granulation tissue gradually covered the wound, and healing occurred, giving an intact abdominal wall. The abdominal rectus muscle fascia from a deceased donor can be used in a definite procedure for closure of the abdominal wall either at the time of transplant or later when a suitable rectus muscle fascia graft becomes available.
由于腹腔容积减少和/或移植物大小与腹腔不匹配,肠道和多脏器移植后可能无法进行腹壁一期关闭。在这类特殊患者中,由于此前多次手术导致腹壁严重瘢痕形成,传统的开腹关闭技术在这些情况下可能并不适用。我们分别介绍了在两名接受尸体供体和活体亲属联合肝脏和小肠移植且无法进行一期关闭的患者中使用非血管化腹直肌筋膜的初步经验。在这两名患者中,均将供体筋膜与受体筋膜相连。在这两种情况下,均没有足够的皮肤覆盖用于关闭,伤口保持开放,并应用了负压敷料。在这两例中,在放置非血管化腹直肌筋膜后的6个月内,伤口收缩,肉芽组织逐渐覆盖伤口并愈合,形成了完整的腹壁。来自尸体供体的腹直肌筋膜可在移植时或之后获得合适的腹直肌筋膜移植物时,用于腹壁关闭的明确手术。