Tsukimoto Shota, Takasugi Yoshihiro, Aoki Risa, Kimura Motoshi, Konishi Tatsuo
Research Associate, Department of Anesthesiology, Kindai University Faculty of Medicine, Osaka, Japan.
Assistant Professor, Department of Anesthesiology, Kindai University Faculty of Medicine, Osaka, Japan.
J Oral Maxillofac Surg. 2019 Oct;77(10):2004-2016. doi: 10.1016/j.joms.2019.04.021. Epub 2019 Apr 25.
The lack of anesthesia to the buccal nerve and an insufficient volume of anesthetic have been reported to be responsible for failed inferior alveolar nerve blocks (IANBs) using the Halsted approach (conventional IANB). We aimed to determine the extent of anesthesia in the buccal nerve innervation area and evaluate the anesthetic efficacy of injecting a larger volume of anesthetic during IANB using the anterior approach (anterior technique) in the clinical setting and with magnetic resonance imaging (MRI) analysis.
The prospective randomized controlled trial included patients scheduled for removal of a mandibular third molar. The primary predictor variables were the approach for IANB (anterior technique vs conventional IANB) and anesthetic dose (1.8 vs 2.7 mL). The primary outcome variables were the extent of anesthesia and the anesthesia success rate, defined as completion without additional anesthesia. The secondary outcome variable was the anesthetic drug distribution related to the pterygomandibular space measured on T2-weighted MRI scans. Statistical independence of the anesthesia success rate among the primary predictor variables was tested with statistical significance set at P ≤ .05.
A total of 108 patients and 10 volunteers were enrolled in the clinical and MRI studies, respectively. Anesthesia of the buccal nerve was evident in patients receiving the anterior technique with 2.7 mL of anesthetic. The success rate of the anterior technique with 2.7 mL of anesthetic (96%) was greater than that with 1.8 mL of anesthetic (67%; P = .0113), and increasing the dose had no effect on the efficacy of conventional IANB (78% vs 81%; P = 1.000). The MRI study showed that the anesthetic was distributed over the anterior surface of the temporalis tendon and in the pterygomandibular space after the anterior technique.
Anesthesia of the buccal nerve using the anterior technique with 2.7 mL of anesthetic solution might contribute to increasing the success rate of anesthesia for removal of mandibular third molars.
据报道,使用霍尔斯特德法(传统下牙槽神经阻滞术)进行下牙槽神经阻滞(IANB)失败的原因是颊神经未得到麻醉以及麻醉剂用量不足。我们旨在确定颊神经支配区域的麻醉范围,并在临床环境中通过磁共振成像(MRI)分析,评估在前入路(前技术)IANB期间注射更大剂量麻醉剂的麻醉效果。
这项前瞻性随机对照试验纳入了计划拔除下颌第三磨牙的患者。主要预测变量为IANB的方法(前技术与传统IANB)和麻醉剂量(1.8 mL与2.7 mL)。主要结局变量为麻醉范围和麻醉成功率,麻醉成功率定义为无需额外麻醉即可完成操作。次要结局变量为在T2加权MRI扫描上测量的与翼下颌间隙相关的麻醉药物分布。对主要预测变量之间麻醉成功率的统计独立性进行了检验,设定统计学显著性为P≤0.05。
临床研究和MRI研究分别共纳入了108例患者和10名志愿者。接受2.7 mL麻醉剂前技术的患者颊神经麻醉明显。2.7 mL麻醉剂前技术的成功率(96%)高于1.8 mL麻醉剂的成功率(67%;P = 0.0113),且增加剂量对传统IANB的效果无影响(78%对81%;P = 1.000)。MRI研究显示,前技术后麻醉剂分布在颞肌腱前表面和翼下颌间隙。
使用2.7 mL麻醉剂溶液的前技术进行颊神经麻醉可能有助于提高下颌第三磨牙拔除术的麻醉成功率。