Department of Neurology, University Hospital Leipzig, Leipzig, Germany.
Department of Neurology, University Hospital Leipzig, Leipzig, Germany.
Auton Neurosci. 2019 Sep;220:102552. doi: 10.1016/j.autneu.2019.05.004. Epub 2019 May 17.
The heart receives parasympathetic and to a lesser degree sympathetic input via the vagus nerve. Here, we investigated whether morphological changes of the cervical vagus nerves (VN) as assessed by high-resolution ultrasound (HRUS) correlated with the autonomic cardiac innervation. Measurement of heart rate variability (HRV) and HRUS of the VNs were performed in 88 healthy subjects (50 female; mean age 56 ± 18 years). HRV parameters and the cross-sectional area (CSA) of the VNs correlated both inversely with age. We also found an inverse correlation between the left VN-CSA and HRV as well as parasympathetic parameters. The results imply an asymmetric parasympathetic (vagal) innervation of the heart.
心脏通过迷走神经接收副交感神经输入，程度较轻时还会接收交感神经输入。在这里，我们研究了通过高分辨率超声（HRUS）评估的颈迷走神经（VN）的形态变化是否与自主心脏神经支配相关。在 88 名健康受试者（50 名女性；平均年龄 56±18 岁）中进行了心率变异性（HRV）和 HRUS 的测量。HRV 参数和 VN 的横截面积（CSA）均与年龄呈负相关。我们还发现左 VN-CSA 与 HRV 以及副交感神经参数呈负相关。结果表明心脏存在不对称的副交感神经（迷走神经）支配。
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