Bach Austin, Villegas Victor M, Gold Aaron S, Shi Wei, Murray Timothy G
Larkin Eye Institute, Miami, Florida 33143, USA.
Bascom Palmer Eye Institute, Miami, Florida 33136, USA.
Int J Ophthalmol. 2019 May 18;12(5):815-819. doi: 10.18240/ijo.2019.05.18. eCollection 2019.
To study ocular axial lengths in pediatric subjects without intraocular pathology.
An Institutional Review Board-approved consecutive retrospective chart review of axial lengths measured in pediatric subjects who underwent examination under anesthesia due to positive family history of retinoblastoma or other inherited ocular disease. Only subjects without any intraocular pathology in either eye were included. Subjects were stratified into age groups. An axial length model using a logarithmic regression algorithm was calculated.
Data from 330 eyes of 165 subjects were included in the study. The mean age at the time of examination was 30.62 (SD 18.04)mo. The steepest increase in axial length was present during the first 10mo of life. After 36mo, there was no statistically significant axial length growth.
This study presents the biggest series of pediatric axial lengths in healthy eyes. The axial length model developed with these data may assist in the diagnosis and management of a wide variety of pediatric ophthalmic diseases.
研究无眼内病变的儿科受试者的眼轴长度。
对因视网膜母细胞瘤或其他遗传性眼病家族史而在麻醉下接受检查的儿科受试者测量的眼轴长度进行一项经机构审查委员会批准的连续回顾性病历审查。仅纳入双眼均无任何眼内病变的受试者。将受试者按年龄组分层。计算使用对数回归算法的眼轴长度模型。
该研究纳入了165名受试者的330只眼的数据。检查时的平均年龄为30.62(标准差18.04)个月。眼轴长度在出生后的前10个月增长最为迅速。36个月后,眼轴长度无统计学上的显著增长。
本研究展示了健康眼睛中最大系列的儿科眼轴长度。利用这些数据建立的眼轴长度模型可能有助于多种儿科眼科疾病的诊断和管理。