Kim Ye Na, Jung Yeonsoon
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Korean J Gastroenterol. 2019 May 25;73(5):260-268. doi: 10.4166/kjg.2019.73.5.260.
The incidence of inflammatory bowel disease (IBD) is increasing rapidly and extra-intestinal manifestations in IBD are also increasing. The prevalence of renal and urinary involvement in IBD ranges from 4-23%. Nephrolithiasis is the most common urinary complication in IBD patients. Parenchymal renal disease is rare but has been well documented and presents most commonly as glomerulonephritis or tubulointerstitial nephritis. The overall morbidity of IBD-related renal manifestations is significant. Therefore, a high index of clinical suspicion and optimal monitoring of the renal function are needed for the early diagnosis and prevention of IBD-related renal manifestations and complications.
炎症性肠病(IBD)的发病率正在迅速上升,IBD的肠外表现也在增加。IBD患者肾脏和泌尿系统受累的患病率在4%至23%之间。肾结石是IBD患者最常见的泌尿系统并发症。实质性肾脏疾病很少见,但已有充分记录,最常见的表现为肾小球肾炎或肾小管间质性肾炎。IBD相关肾脏表现的总体发病率很高。因此,需要高度的临床怀疑指数和对肾功能的最佳监测,以便早期诊断和预防IBD相关的肾脏表现及并发症。