Sugihara Naoya, Watanabe Ryuta, Miura Noriyoshi, Saika Takashi, Ohashi Katsuhisa
Department of Urology Ehime University School of Medicine Toon-shi Japan.
Ohashi Gastroenterology and Proctologic Surgery Clinic Niihama Japan.
IJU Case Rep. 2025 Aug 15;8(5):521-524. doi: 10.1002/iju5.70083. eCollection 2025 Sep.
Lower urinary tract symptoms are common in patients with inflammatory bowel disease; however, the association between ulcerative colitis and chronic prostatitis remains underrecognized.
A 38-year-old man presented with frequent and painful urination unresponsive to the standard treatment of chronic prostatitis. He was subsequently diagnosed with ulcerative colitis based on persistent hematochezia and colonoscopy findings. Treatment with mesalamine and corticosteroids for ulcerative colitis led to improvements in both gastrointestinal and urinary symptoms.
This case suggests a possible link between chronic prostatitis and ulcerative colitis, indicating that prostatitis might represent an extraintestinal manifestation. This association might be explained by shared inflammatory pathways and the prostate's anatomical proximity to the rectum. Clinicians should consider inflammatory bowel disease in male patients exhibiting refractory chronic prostatitis and concurrent gastrointestinal symptoms.
下尿路症状在炎症性肠病患者中很常见；然而，溃疡性结肠炎与慢性前列腺炎之间的关联仍未得到充分认识。
一名38岁男性出现尿频、尿痛，对慢性前列腺炎的标准治疗无反应。随后，根据持续便血和结肠镜检查结果，他被诊断为溃疡性结肠炎。用美沙拉嗪和皮质类固醇治疗溃疡性结肠炎后，胃肠道和泌尿系统症状均有所改善。
该病例提示慢性前列腺炎与溃疡性结肠炎之间可能存在联系，表明前列腺炎可能是一种肠外表现。这种关联可能是由共同的炎症途径以及前列腺与直肠在解剖学上的邻近关系所解释。临床医生应考虑到在患有难治性慢性前列腺炎并伴有胃肠道症状的男性患者中存在炎症性肠病。
