[胃癌丝裂霉素C与氟尿嘧啶或优福定辅助化疗的多医院随机研究（第1部分）。氟尿嘧啶与优福定的比较。北九州癌症化疗合作研究组]
[Multihospital randomized study on adjuvant chemotherapy with mitomycin C and futraful or UFT in gastric cancer (Part 1). Comparison between futraful and UFT. North Kyushu Co-operative Study Group for Cancer Chemotherapy)].
作者信息
Arima S, Simura H, Yamanouchi A, Fukuyama N, Hisatsugu T, Yamamoto H, Ohsato K, Ohkuma R, Nakamura Y, Abe R
出版信息
Gan To Kagaku Ryoho. 1987 Aug;14(8):2524-31.
The present study was undertaken to evaluate the effect of postoperative adjuvant chemotherapy for 232 cases of gastric cancer by a co-operative study group consisting of 21 hospitals. The present paper describes the side effects and the 2-year survival rates in patients. Side effects observed during long-term treatment with Futraful or UFT were considered to be minor, although incidence of toxicity in the UFT group was slightly higher than in the Futraful group. As for 2-year survival, elevated survival was found in stage III cases of poorly differentiated adenocarcinoma. This suggested that UFT is more useful than Futraful.
本研究由21家医院组成的合作研究小组开展，旨在评估232例胃癌患者术后辅助化疗的效果。本文描述了患者的副作用和2年生存率。虽然优福定（UFT）组的毒性发生率略高于替加氟（Futraful）组，但在长期使用Futraful或UFT治疗期间观察到的副作用被认为较小。至于2年生存率，在低分化腺癌的III期病例中发现生存率有所提高。这表明UFT比Futraful更有用。
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