Jouk P S, Rossignol A M, Denis B, Bost M
Arch Mal Coeur Vaiss. 1987 Apr;80(4):538-42.
Echocardiographic examination of a 23 weeks' hydropic fetus disclosed abnormal kinetics of the valve of the foramen ovale. This valve was constantly bulging out, dome-like, into the left atrium, and on TM-mode tracings in transatrial projection the alpha and beta peaks which occur respectively during the opening and closure of the atrioventricular valves throughout fetal life were missing. This anomaly suggested that the ostium secundum was restrictive; the foramen ovale itself was not restrictive. Such abnormal kinetics have not been encountered among 16 other cases of hydrops fetalis of cardiac or other origin, or in a control series of 81 normal fetuses, which clearly shows that the restriction was primitive. At birth, the child presented with aneurysm of the foramen ovale, probably due to the restrictive ostium secundum.
对一名23周大的水肿胎儿进行超声心动图检查发现，卵圆孔瓣的动力学异常。该瓣膜持续呈穹顶状向左心房膨出，在经心房投影的TM模式记录中，整个胎儿期分别在房室瓣开放和关闭时出现的α峰和β峰缺失。这种异常提示继发孔狭窄；卵圆孔本身并不狭窄。在其他16例心脏或其他原因导致的胎儿水肿病例以及81例正常胎儿的对照系列中均未发现这种异常动力学，这清楚地表明这种狭窄是先天性的。出生时，患儿出现卵圆孔瘤，可能是由于继发孔狭窄所致。
