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高压氧治疗创伤性脑损伤和创伤后应激障碍的回顾性病例系列。

Retrospective Case Series of Traumatic Brain Injury and Post-Traumatic Stress Disorder Treated with Hyperbaric Oxygen Therapy.

机构信息

1 Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, USA.

2 Neurological Solutions, Inc., Palm Harbor, USA.

出版信息

Cell Transplant. 2019 Jul;28(7):885-892. doi: 10.1177/0963689719853232. Epub 2019 May 28.

DOI:10.1177/0963689719853232
PMID:31134828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6719491/
Abstract

Returning veterans are frequently diagnosed with traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD). Considering a recent case-controlled study of hyperbaric oxygen therapy (HBOT) reporting a reduction in suicidal ideation, we investigated retrospectively three veterans with chronic TBI/PTSD symptoms who were treated with multiple rounds of HBOT with neurophysiological testing performed before and after treatment. Improvements were detected on parameters within neurocognitive domains, including reductions in suicide-related symptoms. These findings independently confirm that HBOT may be effective in treating specific symptoms of TBI/PTSD that are not currently addressed with existing therapeutic approaches.

摘要

归国老兵常被诊断患有创伤性脑损伤(TBI)和创伤后应激障碍(PTSD)。鉴于最近一项关于高压氧治疗(HBOT)的病例对照研究报告称,这种治疗可减少自杀意念,我们回顾性研究了 3 名患有慢性 TBI/PTSD 症状的老兵,他们接受了多轮 HBOT 治疗,并在治疗前后进行了神经生理学测试。在神经认知领域的参数上都检测到了改善,包括与自杀相关的症状减少。这些发现独立证实,HBOT 可能对治疗目前现有治疗方法无法解决的特定 TBI/PTSD 症状有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/7bc3c7046056/10.1177_0963689719853232-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/eb6ee9405c33/10.1177_0963689719853232-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/df2fd79a4022/10.1177_0963689719853232-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/7bc3c7046056/10.1177_0963689719853232-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/eb6ee9405c33/10.1177_0963689719853232-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/df2fd79a4022/10.1177_0963689719853232-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb0/6719491/7bc3c7046056/10.1177_0963689719853232-fig3.jpg

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Med Gas Res. 2017 Oct 17;7(3):156-174. doi: 10.4103/2045-9912.215745. eCollection 2017 Jul-Sep.
3
Baseline neurological evaluations in a hyperbaric trial of post-concussive syndrome.
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Front Neurol. 2022 Mar 17;13:815056. doi: 10.3389/fneur.2022.815056. eCollection 2022.
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