N. M. Hernandez, R. J. Sierra, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA K. M. Fruth, D.R. Larson, H. M. Kremers, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Clin Orthop Relat Res. 2019 Jun;477(6):1392-1399. doi: 10.1097/CORR.0000000000000702.
There is limited information on the complications and costs of conversion THA after hemiarthroplasty for femoral neck fractures. Previous studies have found that patients undergoing conversion THA experience higher risk complications, but it has been difficult to quantify the risk because of small sample sizes and a lack of comparison groups. Therefore, we compared the complications of patients undergoing conversion THA with strictly matched patients undergoing primary and revision THA.
QUESTIONS/PURPOSES: (1) What are the risks of complications, dislocations, reoperations, revisions and periprosthetic fractures after conversion THA compared with primary and revision THA and how has this effect changed over time? (2) What are the length of hospital stay and hospital costs for conversion THA, primary THA, and revision THA?
Using a longitudinally maintained total joint registry, we identified 389 patients who were treated with conversion THA after hemiarthroplasty for femoral neck fractures between 1985 and 2014. The conversion THA cohort was 1:2 matched on age, sex, and year of surgery to 778 patients undergoing primary THA and 778 patients undergoing revision THA. The proportion of patients having at least 5-year followup was 73% in those who underwent conversion THA, 77% in those who underwent primary THA, and 76% in those who underwent revision THA. We observed a significant calendar year effect, and therefore, compared the three groups across two separate time periods: 1985 to 1999 and 2000 to 2014. We ascertained complications, dislocations, reoperations, revisions and periprosthetic fractures from the total joint registry. Cost analysis was performed using a bottom-up, microcosting methodology for procedures between 2003 and 2014.
Patients who converted to THA between 1985 and 1999 had a higher risk of complications (hazard ratio [HR], 2.3; 95% confidence interval [CI], 1.7-3.1; p < 0.001), dislocations (HR, 2.3; 95% CI, 1.3-4.2; p = 0.007), reoperations (HR, 1.7; 95% CI, 1.2-2.5, p = 0.005), and periprosthetic fractures (HR, 3.8; 95% CI, 2.2-6.6; p < 0.001) compared with primary THA. However, conversion THAs during the 1985 to 1999 time period had a lower risk of reoperations (HR, 0.7; 95% CI, 0.5-1.0; p = 0.037), revisions (HR, 0.6; 95% CI, 0.5-0.9; p = 0.014), and periprosthetic fractures (HR, 0.6; 95% CI, 0.4-0.9; p = 0.007) compared with revision THA. The risk differences across the three groups were more pronounced after 2000, particularly when comparing conversion THA patients with revision THA. Conversion THA patients had a higher risk of reoperations (HR, 1.9; 95% CI, 1.0-3.4; p = 0.041) and periprosthetic fractures (HR, 1.7; 95% CI, 1.0-2.9; p = 0.036) compared with revision THA, but there were no differences in the complication risk (HR, 1.4; 95% CI, 0.9-2.1; p = 0.120), dislocations (HR, 1.5; 95% CI, 0.7-3.2; p = 0.274), and revisions (HR, 1.4; 95% CI, 0.7-3.0; p = 0.373). Length of stay for conversion THA was longer than primary THA (4.7 versus 4.0 days; p = 0.012), but there was no difference compared with revision THA (4.7 versus 4.5 days; p = 0.484). Similarly, total inpatient costs for conversion THA were higher than primary THA (USD 22,662 versus USD 18,694; p < 0.001), but there was no difference compared with revision THA (USD 22,662 versus USD 22,071; p = 0.564).
Over the 30 years of the study, conversion THA has remained a higher risk procedure in terms of reoperation compared with primary THA, and over time, it also has become higher risk compared with revision THA. Surgeons should approach conversion THA as a challenging procedure, and patients undergoing this procedure should be counseled about the elevated risks. Furthermore, hospitals should seek appropriate reimbursement for these cases.
Level III, therapeutic study.
股骨颈骨折行人工髋关节半髋置换术后,行全髋关节置换术(THA)转换的并发症和成本信息有限。先前的研究发现,行转换 THA 的患者经历更高风险的并发症,但由于样本量小且缺乏对照组,因此很难量化风险。因此,我们比较了严格匹配的初次 THA 和翻修 THA 患者行转换 THA 的并发症。
问题/目的:(1)与初次和翻修 THA 相比,转换 THA 后并发症、脱位、再手术、翻修和假体周围骨折的风险如何,以及这种影响随时间如何变化?(2)转换 THA、初次 THA 和翻修 THA 的住院时间和住院费用是多少?
使用纵向维护的全关节登记处,我们确定了 1985 年至 2014 年间因股骨颈骨折行人工髋关节半髋置换术后行转换 THA 的 389 例患者。转换 THA 队列按年龄、性别和手术年份 1:2 与 778 例初次 THA 和 778 例翻修 THA 患者匹配。行转换 THA 的患者中有 73%至少随访 5 年,行初次 THA 的患者中有 77%,行翻修 THA 的患者中有 76%。我们观察到明显的日历年份效应,因此,我们在两个单独的时间段内比较了这三组患者:1985 年至 1999 年和 2000 年至 2014 年。我们从全关节登记处确定了并发症、脱位、再手术、翻修和假体周围骨折。2003 年至 2014 年之间的程序成本分析采用自下而上的微观成本分析方法。
1985 年至 1999 年期间行转换 THA 的患者并发症(危险比 [HR],2.3;95%置信区间 [CI],1.7-3.1;p <0.001)、脱位(HR,2.3;95%CI,1.3-4.2;p = 0.007)、再手术(HR,1.7;95%CI,1.2-2.5,p = 0.005)和假体周围骨折(HR,3.8;95%CI,2.2-6.6;p <0.001)的风险更高。然而,转换 THA 在此期间的再手术(HR,0.7;95%CI,0.5-1.0;p = 0.037)、翻修(HR,0.6;95%CI,0.5-0.9;p = 0.014)和假体周围骨折(HR,0.6;95%CI,0.4-0.9;p = 0.007)的风险低于翻修 THA。2000 年以后,三组之间的风险差异更为明显,特别是在比较转换 THA 患者与翻修 THA 患者时。转换 THA 患者再手术(HR,1.9;95%CI,1.0-3.4;p = 0.041)和假体周围骨折(HR,1.7;95%CI,1.0-2.9;p = 0.036)的风险高于翻修 THA,但并发症风险(HR,1.4;95%CI,0.9-2.1;p = 0.120)、脱位(HR,1.5;95%CI,0.7-3.2;p = 0.274)和翻修(HR,1.4;95%CI,0.7-3.0;p = 0.373)无差异。转换 THA 的住院时间长于初次 THA(4.7 天与 4.0 天;p = 0.012),但与翻修 THA 无差异(4.7 天与 4.5 天;p = 0.484)。同样,转换 THA 的总住院费用高于初次 THA(22662 美元与 18694 美元;p <0.001),但与翻修 THA 无差异(22662 美元与 22071 美元;p = 0.564)。
在 30 年的研究期间,与初次 THA 相比,转换 THA 仍然是一种风险更高的手术,而且随着时间的推移,与翻修 THA 相比,它的风险也更高。外科医生应该将转换 THA 视为一种具有挑战性的手术,而行这种手术的患者应该接受关于风险升高的咨询。此外,医院应该为这些病例寻求适当的报销。
III 级,治疗性研究。