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对于伴有黄疸的不可切除的胆胰肿瘤,采用射频进行腔内消融治疗:一家地区医院的经验。

Intraductal ablation by radiofrequency for inoperable biliopancreatic neoplasms with jaundice: experience at a regional hospital.

机构信息

Medicina Digestiva, Hospital Comarcal Francesc de Borja, España.

Medicina interna, Hospital Comarcal Francesc de Borja, España.

出版信息

Rev Esp Enferm Dig. 2019 Jun;111(6):485-487. doi: 10.17235/reed.2019.5720/2018.

DOI:10.17235/reed.2019.5720/2018
PMID:31140283
Abstract

The current treatment of choice for inoperable and/or unresectable biliopancreatic neoplasms complicated by jaundice is the placement of metal biliary stents. The most common complication is obstruction due to tumor growth. The application of radiofrequency ablation (RFA) is a new minimally invasive technique for the thermal ablation of the tumor tissue that causes biliary stenosis. Experience with RFA is scarce and there are few retrospective studies of clinical cases with a limited number of patients. Thus, there is little information on technical difficulty, safety and short-medium term monitoring. We present three cases, one cholangiocarcinoma and two pancreatic adenocarcinomas, with jaundice due to biliary stenosis. RFA was used with an ELRA catheter during endoscopic retrograde cholangiopancreatography (ERCP). The patients were monitored for ten months in order to assess the difficulty of treatment, efficacy and immediate and medium-term complications.

摘要

对于无法手术和/或不可切除的胆胰肿瘤合并黄疸的患者,目前的治疗选择是放置金属胆道支架。最常见的并发症是由于肿瘤生长导致的阻塞。射频消融(RFA)的应用是一种新的微创技术,用于热消融引起胆道狭窄的肿瘤组织。RFA 的应用经验有限,并且只有少数回顾性研究涉及有限数量的患者。因此,关于技术难度、安全性和短中期监测的信息很少。我们报告了三例因胆道狭窄而出现黄疸的病例,分别为胆管癌和 2 例胰腺腺癌。在逆行胰胆管造影术(ERCP)期间使用 ELRA 导管进行 RFA。对患者进行了十个月的监测,以评估治疗的难度、疗效以及即刻和中期并发症。

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引用本文的文献

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Improving biliary stent patency for malignant obstructive jaundice using endobiliary radiofrequency ablation: experience in 150 patients.采用腔内射频消融术改善恶性梗阻性黄疸患者的胆道支架通畅性:150 例患者的经验。
Surg Endosc. 2022 Mar;36(3):1789-1798. doi: 10.1007/s00464-021-08457-3. Epub 2021 Mar 31.