Steinbach P D, Gruia D G
Klin Monbl Augenheilkd. 1987 Jun;190(6):534-8. doi: 10.1055/s-2008-1050452.
In the study presented here the authors documented 50 patients with chronic glaucoma, aged between 42 and 86, who were followed up on an outpatient basis for a minimum of 3 and a maximum of 6 years. The results can be summarized as follows: 1) treatment with timolol resulted in an average lowering of intraocular pressure by 6 mm Hg, without any fall-off in effect over several years; 2) there was no deterioration in visual fields or visual acuity during treatment with timolol, and in some cases there was an improvement; 3) in the cases of angle-closure glaucoma the therapy was combined with pilocarpine; this resulted in a greater lowering of pressure than that achieved by treatment with timolol alone in cases of open-angle glaucoma.
在本文所介绍的研究中,作者记录了50例慢性青光眼患者,年龄在42岁至86岁之间,这些患者在门诊接受了至少3年、最长6年的随访。结果可总结如下:1)使用噻吗洛尔治疗可使眼压平均降低6毫米汞柱,且数年内效果无任何下降;2)在使用噻吗洛尔治疗期间,视野或视力没有恶化,在某些情况下还有所改善;3)在闭角型青光眼病例中,治疗联合使用了毛果芸香碱;这导致眼压降低幅度比开角型青光眼单独使用噻吗洛尔治疗时更大。