在扁桃体切除术和悬雍垂腭咽成形术患者中使用酮咯酸。

Ketorolac usage in tonsillectomy and uvulopalatopharyngoplasty patients.

机构信息

Department of Otolaryngology & Facial Plastic Surgery, Henry Ford Macomb Hospital, Clinton Township.

Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, Michigan, U.S.A.

出版信息

Laryngoscope. 2020 Apr;130(4):876-879. doi: 10.1002/lary.28077. Epub 2019 May 30.

DOI:10.1002/lary.28077

PMID:31145482

Abstract

OBJECTIVE

Postoperative pain for tonsillectomy with or without adenoidectomy or uvulopalatopharyngoplasty (UPPP) can be severe. Ketorolac is a nonsteroidal anti-inflammatory drug that can be administered for analgesia in these patients. In the literature, ketorolac has been associated with an increased risk of hemorrhage after tonsillectomy with or without adenoidectomy. Many other surgical fields have successfully utilized this medicine for postoperative pain control without increased incidence of hemorrhage. The goal of this study was to analyze the effectiveness of ketorolac after tonsillectomy with or without adenoidectomy or UPPP in adults on postoperative hemorrhage rates.

METHODS

Adult patients older than 18 years of age who underwent tonsillectomy with or without adenoidectomy and UPPP between 2013 and 2018 were assessed to determine hemorrhage rates. Hemorrhage rates were assessed based on patients presenting to the emergency department with complaint of hemorrhage.

RESULTS

There was no significant difference between groups in the postoperative hemorrhage rates (P = .331) or the method of hemorrhage control.

CONCLUSION

Ketorolac did not increase postoperative hemorrhage rates in patients posttonsillectomy with or without adenoidectomy or UPPP.

LEVEL OF EVIDENCE

4 Laryngoscope, 130:876-879, 2020.

摘要

目的

扁桃体切除术联合或不联合腺样体切除术或悬雍垂腭咽成形术（UPPP）后的术后疼痛可能很严重。酮咯酸是一种非甾体抗炎药，可用于这些患者的镇痛。文献中报道，酮咯酸与扁桃体切除术联合或不联合腺样体切除术患者术后出血风险增加有关。许多其他手术领域成功地使用这种药物来控制术后疼痛，而不会增加出血的发生率。本研究的目的是分析在接受扁桃体切除术联合或不联合腺样体切除术或 UPPP 的成年患者中使用酮咯酸对术后出血率的影响。