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人类扁桃体中随年龄变化的细胞变化描述。

Description of age-depending cellular changes in the human tonsil.

作者信息

Siegel G

出版信息

ORL J Otorhinolaryngol Relat Spec. 1978;40(3):160-71. doi: 10.1159/000275400.

DOI:10.1159/000275400
PMID:311460
Abstract

The growth and ageing of tonsils is described by means of the behaviour of the cell count, T cell count, DNA, and organ weight. Proliferation of cells and the influx of recirculating T lymphocytes cause hyperplasia up to the age of 17 approximately, later on the cell count and organ weight decrease again. The number of T cells in cell suspensions from the tonsil is lower than that of blood. Due to the proliferation decrease of B cells and the accumulation of recirculating T lymphocytes, the T cell count in the tonsil increases with advancing years. The tonsil function decrease as a result of this population shift. No influence of the differentiation of T cells by the tonsil can be detected.

摘要

通过细胞计数、T细胞计数、DNA和器官重量的变化来描述扁桃体的生长和老化过程。细胞增殖和再循环T淋巴细胞的流入导致扁桃体增生,这种增生大约持续到17岁,之后细胞计数和器官重量又会下降。扁桃体细胞悬液中的T细胞数量低于血液中的T细胞数量。由于B细胞增殖减少和再循环T淋巴细胞的积累,随着年龄的增长,扁桃体中的T细胞计数会增加。这种细胞群体的变化导致扁桃体功能下降。未检测到扁桃体对T细胞分化有影响。

相似文献

1
Description of age-depending cellular changes in the human tonsil.人类扁桃体中随年龄变化的细胞变化描述。
ORL J Otorhinolaryngol Relat Spec. 1978;40(3):160-71. doi: 10.1159/000275400.
2
Evidence for selective proliferation and histological localisation of B lymphocytes in the human tonsil.人类扁桃体中B淋巴细胞选择性增殖及组织学定位的证据。
ORL J Otorhinolaryngol Relat Spec. 1979;41(3):147-57. doi: 10.1159/000275453.
3
Characterization of clinical tonsil stages by their T-cell count. Immunopathological description of tonsils after a peritonsillar abscess.根据T细胞计数对临床扁桃体阶段进行特征描述。扁桃体周围脓肿后扁桃体的免疫病理学描述。
Acta Otolaryngol. 1978 Nov-Dec;86(5-6):469-72. doi: 10.3109/00016487809107527.
4
[Morphological characteristics of the function of the tonsil as an organ of immunogenesis].[作为免疫发生器官的扁桃体功能的形态学特征]
Arkh Patol. 1983;45(2):83-9.
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[Influence of phytohemagglutinin on changes in the relationship between T- and B-lymphocytes in a cell population isolated from human palatine tonsils].[植物血凝素对从人腭扁桃体分离的细胞群体中T淋巴细胞与B淋巴细胞关系变化的影响]
Zh Mikrobiol Epidemiol Immunobiol. 1977 Mar(3):86-8.
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Localization of T and B lymphocytes in human adenoid, tonsil, appendix and Peyer's patches.T 淋巴细胞和 B 淋巴细胞在人类腺样体、扁桃体、阑尾及派伊尔结中的定位。
Allergol Immunopathol (Madr). 1976 Sep-Oct;4(5):325-32.
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[Immunologic function of the tonsils in relation to immune competent T and B cells in children].[儿童扁桃体与免疫活性T细胞和B细胞相关的免疫功能]
Padiatr Padol. 1980;15(1):11-8.
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Tsitologiia. 1980 Nov;22(11):1351-6.
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Immunological function of tonsils in atopic and nonatopic children, with special reference to E- and EAC-binding lymphocytes.特应性和非特应性儿童扁桃体的免疫功能,特别涉及E和EAC结合淋巴细胞。
Allerg Immunol (Leipz). 1978;24(4):287-93.
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[Comparative study of different types of rosette-forming cells in human peripheral blood and tonsils].[人外周血和扁桃体中不同类型玫瑰花结形成细胞的比较研究]
Zh Mikrobiol Epidemiol Immunobiol. 1979 Jan(1):94-6.

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