白喉：病灶依然存在——来自北阿坎德邦的病例报告

Mohanty Aroop, Bhatia Mohit, Gupta Pratima, Varshney Saurabh, Malhotra Manu, Omar Balram J

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Department of ENT and Head & Neck Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

J Pharm Bioallied Sci. 2019 Apr-Jun;11(2):190-193. doi: 10.4103/jpbs.JPBS_245_18.

Diphtheria is a potentially fatal acute infectious disease caused by toxigenic strains of . It is rare in most developed countries due to routine childhood vaccination. Although Universal Immunization Programme is fully functional in India, several hospital-based surveillance studies over the recent years indicate that cases of this infection do occur among school-going children and adolescents. Poor immunization coverage, failure to take booster doses, and absence of data regarding coverage of booster doses of Diphtheria, Pertussis, and Tetanus vaccine are some of the factors responsible for persistence or possible reemergence of this infection in our country. There are no published reports of diphtheria from the state of Uttarakhand, India, in the recent years. We hereby report a confirmed case of diphtheria from this region.

白喉是由产毒株引起的一种潜在致命的急性传染病。在大多数发达国家，由于儿童常规接种疫苗，这种病很罕见。尽管印度的通用免疫计划已全面实施，但近年来一些基于医院的监测研究表明，在校儿童和青少年中确实会出现这种感染病例。免疫接种覆盖率低、未接种加强剂次以及缺乏关于白喉、百日咳和破伤风疫苗加强剂次接种覆盖率的数据，是我国这种感染持续存在或可能再次出现的一些原因。近年来，印度北阿坎德邦没有白喉的公开报告。我们在此报告该地区一例确诊的白喉病例。