Adesoji A T, Onuh J P, Bagu J, Itohan S A
Department of Microbiology, Federal University Dutsin-Ma, Nigeria.
Afr Health Sci. 2019 Mar;19(1):1385-1392. doi: 10.4314/ahs.v19i1.11.
Multidrug resistant in clinical and environmental samples is a global problem. Data comparing antibiogram of bacteria from these two sources in Nigeria is scarce. Therefore, this study compares antibiogram of isolates from both sources from Dutsin-Ma, Katsina State, Nigeria.
A total of 120 and 150 clinical and aquatic samples respectively were collected for a five months period. Samples were analyzed for isolation of using mannitol salt agar. Bacteria identification were carried out using standard biochemical characterization. Antibiogram of the isolates were determined using disc diffusion methods and comparison with Clinical Laboratory Standard Institute (CLSI)'s Standard.
A total of 120 and 45 were isolated from both clinical and aquatic samples respectively. Highest (100.0%) resistance to cloxacillin was observed among isolates from each source. Clinical and aquatic isolates showed least resistance of 20.0% and 48.0% respectively to gentamicin. All isolated (165) from this studies were multidrug resistant with different antibiotic resistant pattern.
This study revealed that multidrug resistance strains of can be isolated from both clinical and drinking water sources, hence, a public health significance that calls for urgent attention by clinicians and public health workers.
临床和环境样本中的多重耐药是一个全球性问题。在尼日利亚，比较来自这两个来源的细菌抗菌谱的数据很少。因此，本研究比较了来自尼日利亚卡齐纳州杜廷-马这两个来源的分离株的抗菌谱。
在五个月的时间里，分别共收集了120份临床样本和150份水生样本。使用甘露醇盐琼脂对样本进行分析以分离[细菌名称未给出]。采用标准生化特征进行细菌鉴定。使用纸片扩散法测定分离株的抗菌谱，并与临床实验室标准协会（CLSI）的标准进行比较。
分别从临床和水生样本中分离出120株和45株[细菌名称未给出]。在来自每个来源的分离株中，观察到对氯唑西林的耐药率最高（100.0%）。临床和水生分离株对庆大霉素的耐药率分别最低，为20.0%和48.0%。本研究中分离出的所有[细菌名称未给出]（165株）均具有多重耐药性，且耐药模式不同。
本研究表明，[细菌名称未给出]的多重耐药菌株可从临床和饮用水源中分离出来，因此具有公共卫生意义，需要临床医生和公共卫生工作者紧急关注。
