Hanada Tetsuro, Tsuji Natsuki, Miyata Hiromi, Kadogami Daisuke, Seo Koji, Deguchi Mari, Yamamoto Rumiko, Butsuhara Yusuke, Jimi Tomoatsu, Kozono Yuki, Iwami Shuichiro, Terakawa Koichi, Nagano Tadayoshi
Department of Obstetrics and Gynecology, The Tazuke Kofukai, Medical Research Institute, Kitano Hospital, 2-4-20 Kita-Ku, Osaka City, Osaka 530-8480 Japan.
Int Cancer Conf J. 2015 Apr 2;5(1):9-12. doi: 10.1007/s13691-015-0215-9. eCollection 2016 Jan.
Uterine cervical cancer is increasingly prevalent among young Japanese women who are eager to preserve their fertility, and abdominal radical trachelectomy (ART) is often performed in patients with early-stage invasive lesions. Herein we present details of a 27-year-old woman with stage IB1 cervical cancer. Although the patient received ART, histopathological findings revealed a parametrial invasion. Hence, 3 courses of adjuvant chemotherapy with paclitaxel and carboplatin (TC) were administered, and the patient conceived spontaneously 44 months later. Rupture of the membrane occurred at 32 weeks and 4 days, and a 1822 g female baby was delivered by emergency cesarean section. The patient is alive without disease and her child is growing favorably. This case demonstrates the balance between preservation of fertility and curative adjuvant chemotherapy after ART.
子宫颈癌在渴望保留生育能力的年轻日本女性中越来越普遍,对于早期浸润性病变患者常施行腹式根治性宫颈切除术(ART)。在此,我们介绍一名27岁IB1期宫颈癌女性的详细病例。尽管该患者接受了ART,但组织病理学检查结果显示有宫旁浸润。因此,给予了3个疗程的紫杉醇联合卡铂(TC)辅助化疗,患者在44个月后自然受孕。孕32周零4天时胎膜破裂,通过急诊剖宫产分娩出一名体重1822克的女婴。患者无病存活,其孩子生长良好。该病例展示了ART后生育力保留与根治性辅助化疗之间的平衡。