Department of Pathology, Beth Israel Deaconess Medical Center.
Department of Pathology, Harvard Medical School.
Adv Anat Pathol. 2019 Jul;26(4):221-234. doi: 10.1097/PAP.0000000000000237.
Breast and axillary lymph node specimens from breast cancer patients treated with neoadjuvant systemic therapy are being encountered by pathologists with increasing frequency. Evaluation of these specimens presents challenges that differ from those encountered during the examination of other types of breast specimens. This article reviews the key issues regarding the gross and microscopic evaluation of post-neoadjuvant systemic therapy breast and lymph node specimens, and emphasizes the importance of accurate specimen evaluation in assessing treatment response.
越来越多的病理医生遇到了接受新辅助全身治疗的乳腺癌患者的乳腺和腋窝淋巴结标本。这些标本的评估具有与其他类型乳腺标本检查不同的挑战。本文回顾了新辅助全身治疗后乳腺和淋巴结标本的大体和显微镜评估的关键问题，并强调了准确评估标本在评估治疗反应中的重要性。
