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产科肛门括约肌损伤发生率的变化——是否是正式预防计划的结果?

Changing incidence of obstetric anal sphincter injuries-A result of formal prevention programs?

机构信息

Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hillerød, Denmark.

Department of Obstetrics and Gynecology, Copenhagen University Hospital, Herlev, Denmark.

出版信息

Acta Obstet Gynecol Scand. 2019 Nov;98(11):1455-1463. doi: 10.1111/aogs.13672. Epub 2019 Jul 1.

Abstract

INTRODUCTION

Obstetric anal sphincter injuries (OASIS) are serious complications to vaginal delivery causing anal incontinence in 50% of the women in the long term. In Norway, the incidence of OASIS has been significantly reduced from 4%-5% to 1%-2% after implementation of prevention programs focusing on perineal protection. The aim of our study was to evaluate whether implementation of formal prevention programs was associated with a reduced incidence of OASIS over time.

MATERIAL AND METHODS

We performed a historical cohort study, evaluating incidence, change of incidence and risk factors of OASIS during the years 2011-2015 at the four delivery departments in the Capital Region of Denmark. Two of the four departments implemented formal prevention programs in 2012-2013. We performed trend tests and uni- and multivariable analyses, adjusting for important risk factors and calculating interactions between risk factors.

RESULTS

There were 75 173 vaginal deliveries during the study period; of those, 2670 (3.6%) were complicated by OASIS. The incidence of OASIS decreased during the study period from 4.3% (n = 636) in 2011 to 2.6% (n = 399) in 2015. There was a significant decrease in the incidence of OASIS at both the departments with formal prevention programs and those without. After adjustment for other important risk factors of OASIS, we found no significant difference in the risk reduction between departments with and without formal prevention programs.

CONCLUSIONS

We found that the general focus on prevention of OASIS in Denmark was associated with a significant decrease in the incidence of OASIS, but implementation of formal prevention programs did not lead to a further reduction. It is possible that more rigorous interventions at the hospitals with formal prevention programs could have resulted in a significant difference in incidence of OASIS.

摘要

简介

产科肛门括约肌损伤(OASIS)是阴道分娩的严重并发症,会导致 50%的女性长期出现肛门失禁。在挪威,实施专注于会阴保护的预防计划后,OASIS 的发生率从 4%-5%显著降低至 1%-2%。我们的研究目的是评估随着时间的推移,实施正式预防计划是否与 OASIS 发生率的降低相关。

材料和方法

我们进行了一项历史性队列研究,评估了 2011 年至 2015 年在丹麦首都地区的四个分娩部门 OASIS 的发病率、发病率变化和危险因素。其中两个部门在 2012-2013 年实施了正式预防计划。我们进行了趋势检验以及单变量和多变量分析,调整了重要的危险因素,并计算了危险因素之间的相互作用。

结果

研究期间共有 75173 例阴道分娩,其中 2670 例(3.6%)发生 OASIS。在此期间,OASIS 的发病率从 2011 年的 4.3%(n=636)下降至 2015 年的 2.6%(n=399)。在实施正式预防计划的部门和未实施的部门中,OASIS 的发病率均显著下降。在调整了 OASIS 的其他重要危险因素后,我们发现实施正式预防计划的部门与未实施的部门之间在降低风险方面没有显著差异。

结论

我们发现,丹麦普遍关注 OASIS 的预防与 OASIS 发病率的显著下降相关,但实施正式预防计划并未导致发病率的进一步降低。在实施正式预防计划的医院中,更严格的干预措施可能会导致 OASIS 发病率的显著差异。

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