Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Urology. 2019 Sep;131:240-244. doi: 10.1016/j.urology.2019.05.020. Epub 2019 May 28.
To evaluate the effect of a scar-free surgical approach, the modified McIndoe technique, in cases of vaginal agenesis.
Seven patients with Mayer-Rokitansky-Kuster-Hauser syndrome underwent vaginoplasty with the modified McIndoe technique. Mucosa grafts harvested from the vulva were minced into small particles and transplanted to the neovagina.
Epithelization in the neovagina is approximately 20 times in size than that in the mucosa harvested from the donor site. An adequate vaginal length was obtained in all cases, with a minimal change in genital appearance and invisible scars. All 4 sex-active patients reported satisfactory sexual experiences, with spontaneous lubrication during intercourse.
With the modified McIndoe technique, using an autologous micromucosa graft harvested from the vulva and the buccal cavity, we can physiologically reconstruct a new mucosa-lined vagina with minimal sacrifice.
评估无痕手术方法（改良 McIndoe 技术）在阴道闭锁病例中的效果。
7 例 Mayer-Rokitansky-Kuster-Hauser 综合征患者接受了改良 McIndoe 技术的阴道成形术。从外阴采集的黏膜移植物被切成小块并移植到新阴道中。
新阴道的上皮化面积大约是供体部位黏膜的 20 倍。所有病例均获得了足够的阴道长度，生殖器外观变化最小，且无可见疤痕。所有 4 位有性生活的患者均报告了满意的性体验，性交时自然润滑。
通过改良 McIndoe 技术，使用从外阴和口腔采集的自体微小黏膜移植物，我们可以在最小牺牲的情况下，生理性地重建一个新的黏膜衬里阴道。
