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本文引用的文献

1
Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia.美国国立卫生研究院子痫前期预测、预防与治疗研讨会的研究建议
Hypertension. 2019 Apr;73(4):757-766. doi: 10.1161/HYPERTENSIONAHA.118.11644.
2
COLLECT, a collaborative database for pregnancy and placental research studies worldwide.COLLECT,一个面向全球妊娠与胎盘研究的协作数据库。
BJOG. 2019 Jan;126(1):8-10. doi: 10.1111/1471-0528.15393. Epub 2018 Aug 23.
3
Emerging role for dysregulated decidualization in the genesis of preeclampsia.调节异常的蜕膜化在子痫前期发病机制中的新作用。
Placenta. 2017 Dec;60:119-129. doi: 10.1016/j.placenta.2017.06.005. Epub 2017 Jun 9.
4
Collaboration to Understand Complex Diseases: Preeclampsia and Adverse Pregnancy Outcomes.合作以了解复杂疾病:子痫前期与不良妊娠结局
Hypertension. 2016 Apr;67(4):681-7. doi: 10.1161/HYPERTENSIONAHA.115.06133. Epub 2016 Feb 16.
5
Pregnancy and Long-Term Maternal Cardiovascular Health: Progress Through Harmonization of Research Cohorts and Biobanks.妊娠与孕产妇长期心血管健康:通过研究队列与生物样本库的协调实现进展
Hypertension. 2016 Feb;67(2):251-60. doi: 10.1161/HYPERTENSIONAHA.115.06357. Epub 2015 Dec 14.
6
Bioinformatics approach reveals evidence for impaired endometrial maturation before and during early pregnancy in women who developed preeclampsia.生物信息学方法揭示了患先兆子痫的女性在怀孕前及怀孕早期子宫内膜成熟受损的证据。
Hypertension. 2015 Feb;65(2):421-9. doi: 10.1161/HYPERTENSIONAHA.114.04481. Epub 2014 Nov 24.
7
Optimising sample collection for placental research.优化胎盘研究的样本采集
Placenta. 2014 Jan;35(1):9-22. doi: 10.1016/j.placenta.2013.11.005. Epub 2013 Nov 19.
8
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.妊娠期高血压。美国妇产科医师学会妊娠期高血压特别工作组报告
Obstet Gynecol. 2013 Nov;122(5):1122-1131. doi: 10.1097/01.AOG.0000437382.03963.88.
9
If we know so much about preeclampsia, why haven't we cured the disease?如果我们对先兆子痫了解这么多,为什么还没有治愈这种疾病?
J Reprod Immunol. 2013 Sep;99(1-2):1-9. doi: 10.1016/j.jri.2013.05.003. Epub 2013 Jul 25.
10
California Pregnancy-Associated Mortality Review: mixed methods approach for improved case identification, cause of death analyses and translation of findings.加利福尼亚州妊娠相关死亡率审查:改进病例识别、死因分析和研究结果转化的混合方法。
Matern Child Health J. 2014 Apr;18(3):518-26. doi: 10.1007/s10995-013-1267-0.

巨擘妇产科系列:詹姆斯·M·罗伯茨医学博士简介。

Giants in Obstetrics and Gynecology Series: A profile of James M. Roberts, MD.

机构信息

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S. Department of Health and Human Services (NICHD/NIH/DHHS); Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI.

出版信息

Am J Obstet Gynecol. 2019 Jun;220(6):527-536.e1. doi: 10.1016/j.ajog.2019.04.004.

DOI:10.1016/j.ajog.2019.04.004
PMID:31151587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6656378/
Abstract

Dr. James Roberts has made seminal contributions to the understanding of the physiology of pregnancy, and, in particular, to the mechanisms of disease responsible for preeclampsia. His research includes endothelial cell dysfunction, oxidative stress, and other factors that play a role in the pathogenesis of preeclampsia; the use of antioxidant therapy to prevent the syndrome; identification of clinical subtypes of preeclampsia; and assessment of the long-term cardiovascular risk of the disorder. Dr. Roberts is currently an investigator at the Magee-Womens Research Institute and a Professor of Obstetrics, Gynecology, and Reproductive Sciences, Endocrinology, and Clinical and Translational Medicine at the University of Pittsburgh. He was the founding Director of the Magee-Womens Research Institute, and formerly the Elsie Hilliard Hillman Chair in Women’s and Infants’ Health Research at the University of Pittsburgh. For his many original contributions to the understanding of preeclampsia and other obstetrical syndromes, Dr. Roberts is herein recognized as a “Giant in Obstetrics and Gynecology.”

摘要

詹姆斯·罗伯茨博士在理解妊娠生理学方面做出了开创性的贡献,特别是在导致子痫前期的疾病机制方面。他的研究包括内皮细胞功能障碍、氧化应激和其他在子痫前期发病机制中起作用的因素;抗氧化治疗的应用以预防该综合征;识别子痫前期的临床亚型;以及评估该疾病的长期心血管风险。罗伯茨博士目前是 Magee-Womens 研究所的研究员,也是匹兹堡大学妇产科、生殖科学、内分泌学以及临床和转化医学的教授。他曾是 Magee-Womens 研究所的创始主任,也是匹兹堡大学 Elsie Hilliard Hillman 妇女和婴儿健康研究主席。由于他对理解子痫前期和其他产科综合征的许多原创贡献,罗伯茨博士在此被公认为“妇产科巨人”。