Université Libanaise, Faculté des Sciences IV, Laboratoire Energétique et Réactivité à l'Echelle Nanométrique (EREN), Haouch El-Omara, Zahlé, Lebanon.
Univ. Bourgogne Franche-Comté, AgroSup Dijon, PAM UMR A 02.102, Procédés Alimentaires et Microbiologiques, F-21000 Dijon, France.
Food Chem. 2019 Sep 30;293:226-232. doi: 10.1016/j.foodchem.2019.04.108. Epub 2019 Apr 27.
Iprodione is a fungicide widely used in viticulture in most agricultural countries. It was banned recently in the European community because of its carcinogenic and endocrine disrupting characters. In this work, a cheap analytical method able to monitor iprodione in a white wine was developed. Molecularly imprinted sol-gel polymers (MIS) specific to iprodione and using green solvents were synthesized. An experimental design having the following factors (solvent volume and crosslinker quantity) was used to prepare an optimal MIS. In terms of selectivity, the optimal MIS showed the best partition coefficient towards iprodione in a white wine containing four other competing fungicides (procymidone, pyrimethanil, azoxystrobin and iprovalicarb). A solid phase extraction method using the optimal MIS was optimized and applied to analyse iprodione in a white wine. Low detection and quantification limits were reached 11.7 and 39.1 µg/L respectively.
异丙定是一种在大多数农业国家的葡萄种植中广泛使用的杀菌剂。由于其致癌和内分泌干扰特性，最近在欧洲共同体被禁用。在这项工作中，开发了一种廉价的分析方法，能够监测白葡萄酒中的异丙定。合成了对异丙定具有特异性的、使用绿色溶剂的分子印迹溶胶-凝胶聚合物（MIS）。使用具有以下因素（溶剂体积和交联剂数量）的实验设计来制备最佳的 MIS。在选择性方面，最佳的 MIS 显示了在含有其他四种竞争杀菌剂（丙环唑、嘧菌酯、唑菌胺酯和异丙威）的白葡萄酒中对异丙定的最佳分配系数。使用最佳的 MIS 优化了固相萃取方法，并将其应用于白葡萄酒中异丙定的分析。检测限和定量限分别达到 11.7 和 39.1 µg/L。
