Exercise Physiology and Cardiovascular Health Lab, Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Exercise Physiology and Cardiovascular Health Lab, Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Can J Cardiol. 2019 Jun;35(6):712-720. doi: 10.1016/j.cjca.2019.02.024. Epub 2019 Mar 6.
It remains unclear whether cardiac rehabilitation (CR) provides similar benefits to patients with varying levels of body mass index (BMI). We assessed the psychosocial and cardiometabolic health of patients with increased BMI who completed CR.
The records of 582 patients who completed a 3-month outpatient CR program were analyzed. On the basis of their BMI at baseline, patients were categorized as normal (18.5-24.9 kg/m), overweight (25.0-29.9 kg/m), obese (30.0-34.9 kg/m), or severely obese (≥ 35.0 kg/m). Analysis of covariance was used to compare health-related quality of life (ie, Physical Component Summary [PCS] and Mental Component Summary scores), anxiety, depression, and cardiometabolic health indicators between BMI categories after CR.
At baseline, patients with severe obesity, when compared with those with normal BMI, had lower PCS scores (39.7 ± 8.5 vs 44.4 ± 8.4, P < 0.001), elevated levels of anxiety (7.0 ± 3.7 vs 4.8 ± 3.2, P = 0.001) and depression (5.5 ± 4.4 vs 3.4 ± 3.7, P < 0.001), higher glycated hemoglobin A1C (6.5 ± 1.1 vs 5.6 ± 0.7%, P < 0.001) and triglycerides (1.6 ± 0.5 vs 1.1 ± 0.4 mmol/L, P < 0.001), and lower high-density lipoprotein cholesterol (1.1 ± 0.3 vs 1.2 ± 0.4 mmol/L, P = 0.006). After CR, notwithstanding a greater percent weight reduction in obesity (-3.5% ± 6.9% vs +1.1% ± 7.0%, P = 0.002) and severe obesity (-6.5% ± 6.9% vs +1.1% ± 7.0%, P < 0.001), smaller improvements in PCS scores were seen in the obese (4.1 ± 7.4 vs 6.9 ± 7.6, P = 0.011) and severely obese (4.1 ± 7.6 vs 6.9 ± 7.6, P = 0.039) when compared with those with normal BMI.
Poorer psychosocial and cardiometabolic health at baseline coupled with smaller improvements in the PCS score suggest that patients with obesity and severe obesity will benefit from enhanced care in the CR setting.
目前尚不清楚心脏康复(CR)是否能为不同体重指数(BMI)的患者带来相似的益处。我们评估了完成 CR 的超重 BMI 患者的社会心理和心血管代谢健康状况。
分析了 582 名完成 3 个月门诊 CR 项目的患者的记录。根据他们的基线 BMI,患者被分为正常(18.5-24.9kg/m)、超重(25.0-29.9kg/m)、肥胖(30.0-34.9kg/m)或严重肥胖(≥35.0kg/m)。CR 后,采用协方差分析比较 BMI 类别之间的健康相关生活质量(即身体成分综合评分[PCS]和精神成分综合评分)、焦虑、抑郁和心血管代谢健康指标。
基线时,与正常 BMI 相比,严重肥胖患者的 PCS 评分较低(39.7±8.5 比 44.4±8.4,P<0.001),焦虑水平较高(7.0±3.7 比 4.8±3.2,P=0.001)和抑郁(5.5±4.4 比 3.4±3.7,P<0.001),糖化血红蛋白 A1C 较高(6.5±1.1 比 5.6±0.7%,P<0.001)和甘油三酯(1.6±0.5 比 1.1±0.4mmol/L,P<0.001),高密度脂蛋白胆固醇较低(1.1±0.3 比 1.2±0.4mmol/L,P=0.006)。CR 后,尽管肥胖(-3.5%±6.9%比+1.1%±7.0%,P=0.002)和严重肥胖(-6.5%±6.9%比+1.1%±7.0%,P<0.001)患者的体重减轻百分比更大,但肥胖(4.1±7.4 比 6.9±7.6,P=0.011)和严重肥胖(4.1±7.6 比 6.9±7.6,P=0.039)患者的 PCS 评分改善较小。
基线时较差的社会心理和心血管代谢健康状况以及 PCS 评分的较小改善表明,肥胖和严重肥胖患者将受益于 CR 环境中的强化护理。