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常规乳腺 X 线筛查临床实践指南作者的财务利益冲突。

Financial Conflicts of Interest Among Authors of Clinical Practice Guidelines for Routine Screening Mammography.

机构信息

Oklahoma State University, Center for Health Sciences, Tulsa, Oklahoma.

Oklahoma State University, Center for Health Sciences, Tulsa, Oklahoma.

出版信息

J Am Coll Radiol. 2019 Nov;16(11):1598-1603. doi: 10.1016/j.jacr.2019.05.005. Epub 2019 May 29.

DOI:10.1016/j.jacr.2019.05.005
PMID:31152689
Abstract

PURPOSE

Financial conflicts of interest (FCOIs) may influence or undermine the credibility of clinical practice guidelines or society recommendations. Given the wide regard of such publications, understanding the prevalence and extent of FCOIs among their authors is essential.

METHODS

The most current guidelines containing recommendations for breast cancer screening from the US Preventive Services Task Force, American Cancer Society, American College of Obstetricians and Gynecologists, International Agency for Research on Cancer, ACR, and American College of Physicians were retrieved from their respective organizational websites. Industry payments received by authors were then extracted using CMS Open Payments database (OPD), and the values and types of these payments were evaluated. Finally, financial disclosures were compared with open payments.

RESULTS

Among a total of 43 authors and 7 guideline documents, 14 authors (33%) received at least one industry payment according to OPD payment records, whereas a majority of 29 authors (67%) had none. The median total payment from all sources across all breast imaging guidelines was $0 (interquartile range, $0-$84). Four authors (9%) declared at least one significant FCOI, five (12%) received more than $5,000 from a single company in a single year, and one author had a significant FCOI (2%) identified from OPD records but not disclosed within the guideline document.

CONCLUSIONS

These findings suggest that FCOIs likely have little to no influence on the adoption of consensus recommendations regarding routine screening mammography for all cohorts of women.

摘要

目的

财务利益冲突(FCOI)可能会影响或破坏临床实践指南或社会建议的可信度。鉴于此类出版物受到广泛关注,了解其作者的 FCOI 的流行程度和范围至关重要。

方法

从各自的组织网站上检索了美国预防服务工作组、美国癌症协会、美国妇产科医师学会、国际癌症研究机构、ACR 和美国医师学院发布的最新的乳腺癌筛查指南。然后使用 CMS 开放支付数据库(OPD)提取作者收到的行业支付款项,并评估这些款项的价值和类型。最后,将财务披露与开放支付进行比较。

结果

在总共 43 名作者和 7 份指南文件中,根据 OPD 支付记录,有 14 名作者(33%)至少收到了一笔行业支付款项,而大多数作者(67%)没有收到。所有乳腺影像学指南中所有来源的中位数总支付金额为 0 美元(四分位距,0-84 美元)。有 4 名作者(9%)宣布至少存在一项重大 FCOI,5 名作者(12%)在单一年份中从单一公司收到超过 5000 美元的款项,1 名作者的 OPD 记录中存在重大 FCOI(2%)但未在指南文件中披露。

结论

这些发现表明,FCOI 可能对所有女性常规筛查乳房 X 线摄影共识建议的采用几乎没有影响。

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