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溴化物中毒的解毒方法。杂种犬血液透析、血液滤过和血液灌流的比较。

Detoxication methods for bromureide poisoning. Comparison of haemodialysis, haemofiltration and haemoperfusion on bastard dogs.

作者信息

Butte W, Meyer G J, Vollnberg W

出版信息

Arch Toxicol. 1978 Oct 13;41(1):61-7. doi: 10.1007/BF00351770.

Abstract

The efficiency of different detoxication methods for Carbromal intoxications was evaluated on bastard dogs using haemofiltration, haemodialysis and haemoperfusion with coated charcoal and polystyrene resins. Clearance rates and eliminated amounts of Carbromal and bromine were compared. Haemoperfusion is most effective in the elimination of Carbromal and haemodialysis for removal of bromide ions. Haemofiltration was least effective for both and should therefore not be used for the treatment of Carbromal intoxications.

摘要

在杂种犬身上,利用血液滤过、血液透析以及使用包膜活性炭和聚苯乙烯树脂的血液灌流,评估了不同解毒方法对溴米那中毒的疗效。比较了溴米那和溴的清除率及清除量。血液灌流在清除溴米那方面最为有效,而血液透析在清除溴离子方面效果最佳。血液滤过在两者方面效果最差,因此不应用于治疗溴米那中毒。

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