Neil H A, Fairer J G, Coleman M P, Thurston A, Vessey M P
Department of Community Medicine, University of Oxford, Radcliffe Infirmary.
Br Med J (Clin Res Ed). 1987 Aug 8;295(6594):360-2. doi: 10.1136/bmj.295.6594.360.
A cohort of 3769 male anaesthetists resident in the United Kingdom between 1957 and 1983 was followed up for a total of 51,431 person years of observation. All subjects were fellows of the Faculty of Anaesthetists and held full registration with the General Medical Council. With all men in social class I being taken as the standard, the standardised mortality ratio among anaesthetists for all causes of death was 68 (95% confidence interval 59 to 77) and the standardised mortality ratio for all cancers was 50 (95% confidence interval 36 to 67). There was no significant excess mortality from lymphomas or leukaemias, but 16 of the 221 deaths in anaesthetists were due to suicide, giving a standardised mortality ratio of 202 (95% confidence interval 115 to 328). When anaesthetists were compared with all doctors the standardised mortality ratio for suicide was only 114, a nonsignificant excess. These findings confirm that the risk of suicide among anaesthetists is twice as high as among other men in social class I but suggest that the risk does not differ significantly from that among doctors as a whole. There was no evidence of a significant excess risk of cancer, and, in particular, the small excess of cancer of the pancreas reported previously could not be confirmed.
对1957年至1983年间居住在英国的3769名男性麻醉师进行了队列研究，总计观察了51431人年。所有受试者均为麻醉师学院成员，并在英国医学总会进行了全面注册。以社会阶层I中的所有男性作为标准，麻醉师因各种原因死亡的标准化死亡比为68（95%置信区间59至77），所有癌症的标准化死亡比为50（95%置信区间36至67）。淋巴瘤或白血病的死亡率没有显著增加，但麻醉师的221例死亡中有16例死于自杀，标准化死亡比为202（95%置信区间115至328）。当将麻醉师与所有医生进行比较时，自杀的标准化死亡比仅为114，无显著增加。这些发现证实，麻醉师自杀风险是社会阶层I中其他男性的两倍，但表明与全体医生相比，风险没有显著差异。没有证据表明癌症风险有显著增加，特别是之前报道的胰腺癌略有增加的情况无法得到证实。
