Faculty of Health Sciences, Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.
J Matern Fetal Neonatal Med. 2021 Apr;34(7):1127-1132. doi: 10.1080/14767058.2019.1627320. Epub 2019 Jun 16.
The data regarding microbiological and clinical characteristics of Bartholin gland abscesses during pregnancy is limited. Given the hormonal and physiological changes during pregnancy we aimed to examine whether a difference exists in the clinical and microbiological features of Bartholin's gland abscess during pregnancy and the puerperium as compared with nonpregnant patients. In addition, we aim to evaluate whether a Bartholin's gland abscess during pregnancy is associated with adverse pregnancy outcomes.
A retrospective cohort study was conducted, including all women with Bartholin's gland abscess who were treated surgically between the years 2009-2016 in the Soroka University Medical Center. Various demographic, clinical and microbiological characteristics were retrieved and a comparison was made between patients with a Bartholin's gland abscess during pregnancy and the puerperium (study group) as compared with nonpregnant patients (controls). In addition, obstetrical characteristics of patients in the study group were retrieved.
Of the 363 women who were treated surgically, 38 (10.5%) were in the study group. Women in the study group were significantly younger (26.8 versus 32.8 < .001). No differences were found between the groups with regard to the clinical presentation (affected side, fever, leukocytosis and need for antimicrobial treatment) or the selected mode of drainage. In addition, no difference was found in the percentage of positive culture results, nor in the distribution of the pathogens between the groups, in both groups the most common pathogen was . Yet, among the study group, recurrence of the abscess was more common (13.5 versus 2.15% = -.067) as evident by significantly higher recurrent referrals to the emergency department and recurrent hospitalizations (28.9 versus 14.8%, < .05, and 26.3 versus 8.0% < .001, respectively). Of note, fever after the procedures, pain, discharge and bleeding did not differ significantly between groups. No cases of premature rupture of membranes or chorioamnionitis were noted following treatment.
In our cohort, no differences were found between the study groups in the clinical presentation and microbiological features. A significantly higher recurrence rate was noted in the study group. Among pregnant patients no adverse perinatal outcomes were noted.
关于妊娠期间巴氏腺脓肿的微生物学和临床特征的数据有限。鉴于妊娠期间的激素和生理变化，我们旨在检查妊娠和产褥期巴氏腺脓肿的临床和微生物学特征是否与非妊娠患者存在差异。此外，我们旨在评估妊娠期间的巴氏腺脓肿是否与不良妊娠结局相关。
进行了一项回顾性队列研究，纳入了 2009 年至 2016 年间在索罗卡大学医学中心接受手术治疗的所有巴氏腺脓肿患者。检索了各种人口统计学、临床和微生物学特征，并将妊娠和产褥期（研究组）与非妊娠患者（对照组）的巴氏腺脓肿患者进行了比较。此外，还检索了研究组患者的产科特征。
在接受手术治疗的 363 名女性中，有 38 名（10.5%）为研究组。研究组患者明显更年轻（26.8 岁与 32.8 岁，<0.001）。两组在临床表现（受累侧、发热、白细胞增多和需要抗菌治疗）或选择的引流方式方面无差异。此外，两组的阳性培养结果百分比或病原体分布也无差异，两组最常见的病原体均为 。然而，在研究组中，脓肿复发更为常见（13.5%与 2.15%，=0.067），这表现为急诊和再次住院的转诊率显著更高（28.9%与 14.8%，<0.05，和 26.3%与 8.0%，<0.001）。值得注意的是，两组术后发热、疼痛、排液和出血无显著差异。治疗后未发现胎膜早破或绒毛膜羊膜炎病例。
在我们的队列中，研究组在临床表现和微生物学特征方面无差异。研究组的复发率显著更高。在妊娠患者中，未发现不良围产期结局。
