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肥胖在耳鼻喉科疾病中的作用。

Role of Obesity in Otorhinolaryngologic Diseases.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Myongji Hospital, Hanyang University College of Medicine, Goyang, South Korea.

Department of Obstetrics and Gynecology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, South Korea.

出版信息

Curr Allergy Asthma Rep. 2019 Jun 3;19(7):34. doi: 10.1007/s11882-019-0865-3.


DOI:10.1007/s11882-019-0865-3
PMID:31161431
Abstract

PURPOSE OF REVIEW: Obesity is a major public health problem associated with various diseases. Improving obesity control and achieving greater patient satisfaction are critical unmet needs. Various otorhinolaryngologic diseases can have negative effects on quality of life or actual health status depending on their type. Over the past decade, the relationship between obesity and otorhinolaryngologic conditions has been investigated. The purpose of this review was to discuss the relationship between obesity and otorhinolaryngological diseases. RECENT FINDINGS: This is a narrative review on the current state of incidence, effects, and associated mechanisms between obesity and otorhinolaryngologic diseases. In various otologic diseases, otitis media (OM) and hearing loss (HL) are associated with obesity. In rhinologic parts, chronic rhinosinusitis (CRS) and obstructive sleep apnea (OSA) were significantly associated with obesity. Most of these diseases are reported to have higher susceptibility and severity as body mass index (BMI) increases. However, the incidence of head and neck cancer (HNC) was inversely associated with obesity, especially central adiposity. The relevance of obesity in laryngopharyngeal reflux disease (LPR) and allergic rhinitis (AR) has yet to be clarified, and this remains controversial. This review provides a comprehensive overview of the current state of incidence, effects, and associated mechanisms between obesity and otorhinolaryngologic diseases. Various otorhinolaryngological diseases are related to obesity. As obesity can be a negative risk factor in these otorhinolaryngologic diseases, early diagnosis and treatment of these diseases in obese patients will be critical.

摘要

目的综述:肥胖是与多种疾病相关的主要公共卫生问题。改善肥胖控制并提高患者满意度是尚未满足的关键需求。各种耳鼻喉疾病根据其类型可能对生活质量或实际健康状况产生负面影响。在过去的十年中,肥胖与耳鼻喉状况之间的关系已经得到了研究。本文旨在讨论肥胖与耳鼻喉科疾病之间的关系。

最近的发现:这是一篇关于肥胖与耳鼻喉科疾病之间目前发病率、影响和相关机制的叙述性综述。在各种耳科疾病中,中耳炎(OM)和听力损失(HL)与肥胖有关。在鼻科学部分,慢性鼻-鼻窦炎(CRS)和阻塞性睡眠呼吸暂停(OSA)与肥胖显著相关。这些疾病中的大多数报告称,随着体重指数(BMI)的增加,其易感性和严重程度增加。然而,头颈部癌症(HNC)的发病率与肥胖呈负相关,尤其是中央肥胖。肥胖与喉咽反流病(LPR)和过敏性鼻炎(AR)的相关性尚未阐明,这方面仍存在争议。本综述提供了肥胖与耳鼻喉科疾病之间目前发病率、影响和相关机制的全面概述。各种耳鼻喉疾病都与肥胖有关。由于肥胖可能是这些耳鼻喉疾病的负面风险因素,因此对肥胖患者的这些疾病进行早期诊断和治疗将至关重要。

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[3]
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Allergy Asthma Clin Immunol. 2023-12-19

[4]
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[5]
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Clin Exp Otorhinolaryngol. 2023-2

[6]
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Cureus. 2022-9-10

[7]
FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma.

Pharmgenomics Pers Med. 2021-9-28

[8]
The changes of clinical and histological characteristics of chronic rhinosinusitis in 18 years: Was there an inflammatory pattern shift in southern China?

World Allergy Organ J. 2021-4-16

[9]
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population.

Diagnostics (Basel). 2020-12-25

[10]
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本文引用的文献

[1]
Association of Obesity with Hearing Impairment in Adolescents.

Sci Rep. 2019-2-12

[2]
Obstructive sleep apnea in children and adolescents with and without obesity.

Eur Arch Otorhinolaryngol. 2019-3

[3]
Role of Leptin/Osteopontin Axis in the Function of Eosinophils in Allergic Rhinitis with Obesity.

Mediators Inflamm. 2018-10-24

[4]
Leptin/Osteopontin Axis Regulated Type 2T Helper Cell Response in Allergic Rhinitis with Obesity.

EBioMedicine. 2018-6-7

[5]
Associations of Current Wheeze and Body Mass Index with Perennial and Seasonal Allergic Rhinitis in Young Adults.

Int Arch Allergy Immunol. 2018-5-16

[6]
Association of Metabolic Syndrome With Sudden Sensorineural Hearing Loss.

JAMA Otolaryngol Head Neck Surg. 2018-4-1

[7]
Association of leptin with disease severity and inflammation indicators in Chinese obese children with allergic rhinitis.

Pediatr Allergy Immunol. 2018-1-25

[8]
Guideline Recommendations for Obesity Management.

Med Clin North Am. 2018-1

[9]
Asthma, GERD and Obesity: Triangle of Inflammation.

Indian J Pediatr. 2017-11-11

[10]
Relationship between chronic otitis media with effusion and overweight or obesity in children.

J Laryngol Otol. 2017-10

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