Dryden M S
Department of Microbiology, St Thomas's Hospital, London.
J R Soc Med. 1987 Aug;80(8):480-1. doi: 10.1177/014107688708000807.
A bacteriological survey was undertaken on clinically infected traumatic wounds amongst a group of young and fit Operation Raleigh members, who were living and working in a remote area of Costa Rican rain forest. All infected wounds were swabbed before treatment and, where possible, at intervals during treatment. Swabs were also obtained from the nose and throat of each patient. All swabs were stored by desiccation in sterile silica gel for culture at a later date. Culture revealed a high rate of isolation of Bacillus cereus from the wounds. The organism was commonly isolated in pure and heavy growth. Contamination by B. cereus was considered and excluded experimentally. Preliminary toxological studies have shown that the majority of the isolates produce a necrotic exotoxin, in keeping with the clinical findings. These results suggest that B. cereus caused significant sepsis in this series of traumatic wounds.
对一群年轻健康的罗利行动成员的临床感染创伤伤口进行了细菌学调查，这些成员在哥斯达黎加雨林的偏远地区生活和工作。所有感染伤口在治疗前进行拭子采样，并且在可能的情况下，在治疗期间定期采样。还从每位患者的鼻子和喉咙采集了拭子。所有拭子通过干燥保存在无菌硅胶中，以便日后培养。培养结果显示，伤口中蜡样芽孢杆菌的分离率很高。该菌通常以纯培养和大量生长的形式被分离出来。考虑到蜡样芽孢杆菌的污染并通过实验排除了这种可能性。初步毒理学研究表明，大多数分离株产生坏死性外毒素，这与临床发现一致。这些结果表明，蜡样芽孢杆菌在这一系列创伤伤口中引起了严重的败血症。
