Khan Ruqayya Naheed, Parvaiz Muhammad Asad, Khan Amina Iqbal, Loya Asif
FCPS, SKMCH, Pakistan.
SKMCH, Pakistan.
Int J Surg Case Rep. 2019;59:152-155. doi: 10.1016/j.ijscr.2019.05.037. Epub 2019 May 28.
Accessory or ectopic breast tissue is an aberration of normal breast development. It is known to be a rare entity present anywhere along the embryologic mammary streak or milk line but more common in axilla.
We report a case of 36 year old female with accessory breast carcinoma who presented with a progressive lump in her left axilla for 1 year. On examination a 2 cm solitary mass was palpable in axilla. Ultrasound confirmed a 19 mm mass with no other lesion in breast and axilla. Core biopsy showed invasive ductal carcinoma. She was discussed in multidisciplinary board meeting and was offered upfront surgery with excision of accessory breast tissue and sentinel lymph node biopsy. Axillary lymph node dissection was omitted following ACOSG Z0011 criteria. She was offered adjuvant chemotherapy and radiation post operatively along with endocrine treatment as she was hormone receptor positive.
Accessory breast development is hormone dependent just like normal breast. Breast cancer in accessory breast tissue is very rare. The incidence is around 6%. Most common pathology is invasive ductal carcinoma (50-75%). The most common location is axilla (60-70%) although it can present in other less common locations like infra-mammary region (5-10%) and rarely in thighs, perineum, groin, and vulva.
Since accessory axillary breast tissue is out of the image of screening breast examination, it is necessary for the oncologists to be aware of this entity and associated pathologies. Their preventive excision in high risk women can also be considered.
副乳或异位乳腺组织是正常乳腺发育的一种异常情况。已知它是一种罕见的实体,可出现在胚胎乳腺嵴或乳线的任何部位,但在腋窝更为常见。
我们报告一例36岁患有副乳癌的女性,她左侧腋窝出现进行性肿块1年。检查时,在腋窝可触及一个2厘米的孤立肿块。超声检查证实有一个19毫米的肿块,乳腺和腋窝无其他病变。核心活检显示为浸润性导管癌。在多学科委员会会议上对该病例进行了讨论,并为她提供了先行手术,切除副乳组织并进行前哨淋巴结活检。根据美国外科医师学会肿瘤学组(ACOSG)Z0011标准,省略了腋窝淋巴结清扫术。由于她激素受体阳性,术后为她提供了辅助化疗、放疗以及内分泌治疗。
副乳的发育与正常乳腺一样依赖激素。副乳组织中的乳腺癌非常罕见。发病率约为6%。最常见的病理类型是浸润性导管癌(50 - 75%)。最常见的部位是腋窝(60 - 70%),尽管它也可出现在其他不太常见的部位,如乳腺下区域(5 - 10%),很少出现在大腿、会阴、腹股沟和外阴。
由于腋窝副乳组织不在乳腺筛查检查的视野范围内,肿瘤学家有必要了解这一实体及其相关病理情况。对于高危女性,也可考虑预防性切除。