Modolin Miguel Luiz Antônio, Cintra Wilson, Rocha Rodrigo Itocazo, Camargo Cristina Pires, Giuliani Nádia de Rosso, Souza Heraldo Possolo de, Barbeiro Hermes Vieira, Gemperli Rolf
Clinics Hospital, Medical School, Universidade de São Paulo, Brazil.
Clinics Hospital, Medical School, USP, São Paulo, SP, Brazil.
Acta Cir Bras. 2019;34(5):e201900506. doi: 10.1590/s0102-865020190050000006. Epub 2019 Jun 3.
To evaluate the serum variations of Interleukins (Il) and CPR of abdominoplasties in post-bariatric patients and, to equate the homeostasis (HOMA) from the variations of glycemia and insulin to evolute the metabolic modifications.
Fourteen women were submitted to abdominoplasties with weight loss after a gastroplasty. Levels of IL4, IL6, IL10, CRP, glycemia and insulin were obtained during the pre-operative, trans-operative, 24 hours post, 7th and 14th postoperative days.
The IL4 was higher at 24 hours post-surgery, and after a moderate decrease, it remained high until the 14th day. The IL6 and CRP had an expressive increase during the trans-operative period. The CRP remained high, and the IL6 decreased on the 7th and 14th days. The IL10 increased during the transoperative period, and it posteriorly decreased to lower levels in comparison to the pre-operative period. The already increased glycemia during the pre-operative period was even higher during the trans-operative and then, returned to preliminary values on the 7th and 14th days after surgery. The HOMA accompanied the insulin.
The inflammatory and glycemic serum levels decrease after abdominiplasty in obese post-bariatric patients.
评估减重术后接受腹壁成形术患者的白细胞介素（Il）和CPR的血清变化，并根据血糖和胰岛素的变化来评估内稳态（HOMA），以了解代谢改变情况。
14名女性在胃成形术后体重减轻后接受了腹壁成形术。在术前、术中、术后24小时、术后第7天和第14天获取IL4、IL6、IL10、CRP、血糖和胰岛素水平。
IL4在术后24小时升高，在适度下降后，直到第14天仍保持较高水平。IL6和CRP在手术期间有明显升高。CRP持续保持高水平，而IL6在第7天和第14天下降。IL10在手术期间升高，随后与术前相比降至较低水平。术前已经升高的血糖在手术期间更高，然后在术后第7天和第14天恢复到初始值。HOMA与胰岛素变化一致。
减重术后肥胖患者接受腹壁成形术后，炎症和血糖血清水平降低。
