Pálmarsdóttir Rakel, Kiesbye Øvlisen Andreas, Severinsen Marianne Tang, Glimelius Ingrid, Smedby Karin E, El-Galaly Tarec
Department of Hematology, Aalborg University Hospital, Aalborg, Denmark.
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Leuk Lymphoma. 2019 Dec;60(13):3116-3131. doi: 10.1080/10428194.2019.1613538. Epub 2019 Jun 6.
Hodgkin lymphoma is a highly curable disease with a peak incidence in young adulthood at times where education, family, and social relations are established. We performed a systematic literature review to assess the impact of Hodgkin lymphoma on the socioeconomic status of adolescent and adult survivors (including educational achievements, occupational aspects, marriage, and parenthood). In total, 39 articles were included. Overall, 26-36% of survivors perceived Hodgkin lymphoma as negatively affecting their socioeconomic status. Studies consistently found educational achievements in line with general population. Employment rates for survivors were comparable to the general population, but lower than before Hodgkin lymphoma diagnosis, with a post-diagnosis increase in disability pension and early retirement. Employed survivors encountered problems related to physical restrictions and recruitment. Marriage and parenthood were not substantially affected. In conclusion, current studies suggest acceptable socioeconomic outcomes following a Hodgkin lymphoma diagnosis but the use of standardized reporting methods hampers comparability across studies.
霍奇金淋巴瘤是一种治愈率很高的疾病,在青年期发病率达到峰值,而这个时期正是人们建立教育、家庭和社会关系的阶段。我们进行了一项系统的文献综述,以评估霍奇金淋巴瘤对青少年和成年幸存者社会经济状况的影响(包括教育成就、职业方面、婚姻和生育)。总共纳入了39篇文章。总体而言,26%至36%的幸存者认为霍奇金淋巴瘤对他们的社会经济状况产生了负面影响。研究一致发现,幸存者的教育成就与普通人群相当。幸存者的就业率与普通人群相当,但低于霍奇金淋巴瘤诊断前的水平,诊断后残疾抚恤金和提前退休的人数有所增加。就业的幸存者遇到了与身体限制和招聘相关的问题。婚姻和生育没有受到实质性影响。总之,目前的研究表明,霍奇金淋巴瘤诊断后的社会经济结果尚可,但标准化报告方法的使用妨碍了各研究之间的可比性。