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一个家族中三名成员出现输血交叉配血不合多凝集现象。

Tx polyagglutination in three members of one family.

作者信息

Wolach B, Sadan N, Bird G W, Moulds J J, Bar-Shany S, Ben-Porath D, Levene N A, Sela R, Levene C

机构信息

Department of Pediatrics, Meir General Hospital, Israel.

出版信息

Acta Haematol. 1987;78(1):45-7. doi: 10.1159/000205835.

DOI:10.1159/000205835
PMID:3116808
Abstract

A case of acute haemolytic anaemia is described in a child. Tx polyagglutination of his red cells was observed, but no direct association with the anaemia could be proved. Polyagglutination was suspected because of irregularities in the AB0 blood grouping. Confirmation of the cryptantigen Tx was made when the patient's red cells were tested with lectins including Arachis hypogaea, Glycine soja, and Vicia cretica. Examination of family members showed Tx polyagglutination on the red cells of 2 siblings. The Tx polyagglutination was a transient phenomenon lasting 4-5.5 months, and could have been caused as the result of some unidentified bacterial or viral infection. Guidelines for transfusion therapy are suggested in patients in whom polyagglutination is recognised.

摘要

本文描述了一名儿童急性溶血性贫血病例。观察到其红细胞存在Tx多凝集现象,但无法证明与贫血有直接关联。由于ABO血型分组存在异常,怀疑有多凝集现象。当用包括花生、大豆和野豌豆在内的凝集素检测患者红细胞时,证实了隐匿抗原Tx的存在。对家庭成员的检查显示,2名兄弟姐妹的红细胞上存在Tx多凝集现象。Tx多凝集是一种持续4 - 5.5个月的短暂现象,可能是由某种不明细菌或病毒感染引起的。文中针对识别出多凝集现象的患者提出了输血治疗指南。

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引用本文的文献

1
Polyagglutinability phenomenon: a case report and review of the literature.多凝集现象:一例病例报告及文献复习。
J Med Case Rep. 2023 Aug 16;17(1):349. doi: 10.1186/s13256-023-04072-z.