远红至近红外区碳点：制备及在生物技术中的应用。
Far-Red to Near-Infrared Carbon Dots: Preparation and Applications in Biotechnology.
机构信息
Institute of Chemical Biology and Clinical Application at the First Affiliated Hospital, Henan Joint International Research Laboratory of Green Construction of Functional Molecules and Their Bioanalytical Applications, College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, P. R. China.
School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
出版信息
Small. 2019 Nov;15(48):e1901507. doi: 10.1002/smll.201901507. Epub 2019 Jun 6.
As novel fluorescent nanomaterials, carbon dots (CDs) exhibit excellent photostability, good biocompatibility, and high quantum yield (QY). Their superior properties make them promising candidates for biomedical assays and therapy. Among them, the red-emission (>600 nm) CDs have attracted increasing attention in the past years due to their little damage to the biological matrix, deep tissue penetration, and minimum autofluorescence background of biosamples. This Review, summarizes the recent progress of far-red to near-infrared (NIR) CDs from the preparation and their biological applications. The challenges in designing far-red and NIR CDs and their further applications in biomedical fields are also discussed.
作为新型荧光纳米材料，碳点（CDs）表现出优异的光稳定性、良好的生物相容性和高量子产率（QY）。它们的优越性能使它们成为生物医学分析和治疗的有前途的候选者。在这些材料中，近年来，由于红色发射（>600nm）的 CDs 对生物基质的损伤较小、对深层组织的穿透力强以及生物样品的自发荧光背景最小，因此引起了越来越多的关注。这篇综述总结了近年来远红到近红外（NIR）CDs 的制备及其生物应用方面的最新进展。还讨论了设计远红和 NIR CDs 及其在生物医学领域进一步应用的挑战。
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