一名患有高同型半胱氨酸血症儿童的视网膜中央静脉阻塞：病例报告。
Central retinal venous occlusion in a child with hyperhomocysteinemia: A case report.
作者信息
Liu Zhengfeng, Pan Xuemei, Jiang Wenjun, Bi Hongsheng
机构信息
Shandong University of Traditional Chinese Medicine.
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine.
出版信息
Medicine (Baltimore). 2019 Jun;98(23):e15813. doi: 10.1097/MD.0000000000015813.
RATIONALE
To report a rare case of 8-year-old girl patient with central retinal venous occlusion (CRVO) with hyperhomocysteinemia.
PATIENT CONCERNS
The patient had a 2-year history on painless visual loss in the left eye.
DIAGNOSES
All examination results were within normal limits except plasma homocysteine (HCY). Fluorescein angiography (FA) confirmed peripheral capillary non-perfusion (CNP) in the left eye, and OCT showed macular edema. The girl patient was diagnosed as CRVO.
INTERVENTIONS
Based on all of the test results, laser photocoagulation was performed at peripheral capillary non-perfusion (NP). Ranibizumab was injected into virtreous cavity to reduce the macular edema. Oral folic acid, vitamin B12, and vitamin B6 were performed to the girl.
OUTCOMES
After 13 months, the girl visual acuity recovered to 20/100 in the left eye.
LESSONS
All eye examinations should be performed in young patients, and they should undergo treatments immediately after is diagnosed as CRVO.
理由
报告一例罕见的8岁女性中央视网膜静脉阻塞（CRVO）合并高同型半胱氨酸血症患者。
患者情况
该患者有2年左眼无痛性视力丧失病史。
诊断
除血浆同型半胱氨酸（HCY）外，所有检查结果均在正常范围内。荧光素血管造影（FA）证实左眼周边毛细血管无灌注（CNP），光学相干断层扫描（OCT）显示黄斑水肿。该女童患者被诊断为CRVO。
干预措施
根据所有检查结果，对周边毛细血管无灌注（NP）区域进行激光光凝治疗。向玻璃体腔注射雷珠单抗以减轻黄斑水肿。给该女童口服叶酸、维生素B12和维生素B6。
结果
13个月后，该女童左眼视力恢复到20/100。
经验教训
对于年轻患者应进行全面眼部检查，确诊为CRVO后应立即接受治疗。
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