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进展期胃癌开放胃切除术与腹腔镜手术的比较。

Comparison of open gastrectomy and the laparoscopic procedure in advanced gastric cancer.

作者信息

Panduro-Correa V, Dámaso-Mata B, Loza-Munárriz C, Herrera-Matta J J, Arteaga-Livias K

机构信息

Facultad de Medicina, Universidad Nacional Hermilio Valdizán, Huánuco, Perú; Universidad Peruana Cayetano Heredia, Lima, Perú.

Facultad de Medicina, Universidad Nacional Hermilio Valdizán, Huánuco, Perú.

出版信息

Rev Gastroenterol Mex (Engl Ed). 2020 Jan-Mar;85(1):32-41. doi: 10.1016/j.rgmx.2019.01.004. Epub 2019 Jun 3.

DOI:10.1016/j.rgmx.2019.01.004
PMID:31171390
Abstract

INTRODUCTION AND AIM

Gastric cancer is one of the most frequent neoplasias in Peru and worldwide, with surgery as the only potentially curative or palliative treatment. Laparoscopic gastrectomy is the most frequent alternative surgical technique utilized, but one of its main drawbacks is the technical difficulty involved in perigastric lymphadenectomy. The aim of the present study was to evaluate the clinical and surgical characteristics, postoperative complications, and survival rate in patients with advanced gastric cancer that underwent open gastrectomy or laparoscopic gastrectomy at the Hospital Nacional P.N.P "Luis N. Sáenz" in Lima, Peru, within the time frame of 2005 to 2014.

MATERIALS AND METHODS

An analytic, longitudinal, retrospective cohort study was conducted on 482 patients that underwent surgery for gastric cancer, within the time frame of January 2005 to December 2014. The clinical, epidemiologic, and postoperative characteristics were evaluated, and a survival analysis was carried out.

RESULTS

Of the 475 patients included in the study, 236 underwent open gastrectomy and 239 had laparoscopic gastrectomy. Median follow-up time was 61.9 months in the open surgery group and 46.7 months in the laparoscopy group. There were fewer postoperative complications in the laparoscopy group and no statistically significant difference between the two groups in relation to the survival analysis.

CONCLUSIONS

In our study, laparoscopic gastrectomy resulted in fewer postoperative complications, compared with the open procedure, but did not modify overall survival during the follow-up period.

摘要

引言与目的

胃癌是秘鲁乃至全球最常见的肿瘤之一,手术是唯一可能治愈或缓解病情的治疗方法。腹腔镜胃切除术是最常用的替代手术技术,但其主要缺点之一是胃周淋巴结清扫术存在技术难度。本研究的目的是评估2005年至2014年期间在秘鲁利马的国家警察医院“路易斯·N·萨恩斯”接受开腹胃切除术或腹腔镜胃切除术的晚期胃癌患者的临床和手术特征、术后并发症及生存率。

材料与方法

对2005年1月至2014年12月期间接受胃癌手术的482例患者进行了一项分析性、纵向、回顾性队列研究。评估了临床、流行病学和术后特征,并进行了生存分析。

结果

在纳入研究的475例患者中,236例行开腹胃切除术,239例行腹腔镜胃切除术。开腹手术组的中位随访时间为61.9个月,腹腔镜组为46.7个月。腹腔镜组术后并发症较少,两组在生存分析方面无统计学显著差异。

结论

在我们的研究中,与开腹手术相比,腹腔镜胃切除术导致的术后并发症较少,但在随访期间并未改变总体生存率。

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