丙戊酸单药治疗导致的脑假性萎缩
Pseudoatrophy of the brain with valproic acid monotherapy.
作者信息
McLachlan R S
机构信息
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
出版信息
Can J Neurol Sci. 1987 Aug;14(3):294-6. doi: 10.1017/s0317167100026640.
PMID:3117347
Abstract
A patient is described who, while on valproic acid monotherapy, developed reversible shrinkage of the brain, documented by computerized tomography with associated cognitive deficit. Although pseudoatrophy has been reported with steroid therapy, this is the first implication of an anticonvulsant drug in the etiology of that condition.
摘要
本文描述了一名患者，在接受丙戊酸单药治疗时出现了脑可逆性萎缩，计算机断层扫描证实了这一情况，同时伴有认知缺陷。虽然已有报道称类固醇治疗会出现假性萎缩，但这是抗惊厥药物首次被认为与该病症的病因有关。
Zotero 插件