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[氟伏沙明的致癫痫作用。关于一例病例]

[Epileptogenic action of fluvoxamine. Apropos of a case].

作者信息

Lôo H, Piau A, Galinowski A, Olié J P

机构信息

Service Hospitalo-Universitaire de Santé Mentale et de Thérapeutique, Faculté Paris Cochin, C.H.S. Sainte-Anne.

出版信息

Encephale. 1987 Jul-Aug;13(4):231-2.

PMID:3117516
Abstract

A case of status epilepticus with transient motor deficit is reported in a 66 year old male treated with fluvoxamine. Fluvoxamine is supposed to induce few epileptic seizures. The patient had no previous history of epilepsy. Two factors seem to have favoured the occurrence of epilepsy: presence of an incipient arteriopathic impairment, cortical and subcortical brain atrophy and perhaps drug overdosage causing a tremor in the days before the epileptic fit.

摘要

本文报告了一例66岁男性服用氟伏沙明后出现癫痫持续状态并伴有短暂运动功能缺损的病例。氟伏沙明被认为很少诱发癫痫发作。该患者既往无癫痫病史。有两个因素似乎促使了癫痫的发生:存在早期动脉病变损害、皮质和皮质下脑萎缩,以及可能在癫痫发作前几天因药物过量导致震颤。

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