Karakasi Maria Valeria, Markopoulou Maria, Alexandri Maria, Douzenis Athanasios, Pavlidis Pavlos
Laboratory of Forensic Sciences, Democritus University of Thrace, School of Medicine, GR 68100, Dragana, Alexandroupolis, Greece; Adult Psychiatry, Psychiatric Department, George Papanikolaou General Hospital of Thessaloniki, GR 57010, Exochi, Asvestochorion, Thessaloniki, Greece.
Department of Forensic Psychiatry, Psychiatric Hospital of Thessaloniki, GR 56429, Stavroupolis, Thessaloniki, Greece.
J Forensic Leg Med. 2019 Aug;66:8-24. doi: 10.1016/j.jflm.2019.05.019. Epub 2019 May 31.
The present paper aims to describe a case of a schizophrenia spectrum disorder relapse leading to attempted murder, review literature, and investigate the epidemiological data and expression of violent behavior among Capgras-related incidents. 109 case reports deriving from various scientific areas dating from 1971 to 2017 were evaluated and juxtaposed with an equivalent comparison group of random psychiatry inpatients, who were examined for the same variables. Quantitative and qualitative differences were observed between samples. High level of interpersonal violence was disclosed among Capgras-related incidents, especially towards the main care-givers, with higher propensity among male patients. Homicidal behavior was also expressed in higher levels among male patients experiencing the Capgras delusion. A multidisciplinary approach is vital for the optimal management of these incidents. Further research on the pathophysiology of Capgras delusion with the utilization of functional imaging techniques is of exceptional significance for the understanding of issues of neuroscience.
本文旨在描述一例精神分裂症谱系障碍复发导致企图谋杀的病例，回顾相关文献，并调查与卡普格拉综合征相关事件中暴力行为的流行病学数据及表现。对1971年至2017年来自不同科学领域的109例病例报告进行了评估，并与一组随机抽取的精神病住院患者进行了同等比较，对这些患者进行了相同变量的检查。样本之间观察到了定量和定性的差异。在与卡普格拉综合征相关的事件中，人际暴力程度较高，尤其是针对主要照顾者，男性患者的倾向更高。在患有卡普格拉妄想的男性患者中，杀人行为的发生率也更高。多学科方法对于这些事件的最佳管理至关重要。利用功能成像技术对卡普格拉妄想的病理生理学进行进一步研究对于理解神经科学问题具有特殊意义。
