Hospital Universitario Germans Trías I Pujol, Badalona, Spain.
Hospital Universitario Virgen del Rocío, Seville, Spain.
J Affect Disord. 2019 Sep 1;256:176-182. doi: 10.1016/j.jad.2019.05.078. Epub 2019 May 31.
High rates of suicidal behaviour (SB) have been found in first episode psychosis (FEP) patients. It has been suggested that the presence of multiple suicide attempts (mSA) increases the risk of later SA and the risk of eventual death by suicide.
Our main objective was to study the baseline factors associated with the presence of mSA during the first year after FEP. In addition, a second aim was to find out whether there were any differences between single and multiple suicide attempters in the timing of the first SA after FEP.
A total of 65 FEP patients were evaluated. The presence of SAs were recorded at two different times after FEP. Bivariate and multivariate analyses were performed to explore the relationship between SA with sociodemographic and clinical variables.
Multiple linear regression showed that mSA was associated with the presence of increased symptom severity (B = 0.35; t = 3.67; p < 0.01) and errors in first-order false-belief task (B = 0.48; t = 2.11; p = 0.04). There were significant differences in the timing of first SA after FEP between multiple and single suicide attempters.
Theory of mind impairments along with more severe symptoms during the first contact with mental health services for psychotic symptoms appeared to be important predictors of mSA. On the other hand, multiple suicide attempters tend to make a first SA after FEP earlier than single suicide attempters. These results could contribute to the implementation of preventive suicidal programs, however they must be confirmed by additional research.
在首发精神病患者中发现自杀行为(SB)的发生率很高。有人认为,多次自杀企图(mSA)的存在增加了以后发生 SB 的风险和最终自杀死亡的风险。
我们的主要目的是研究首发精神病(FEP)后第一年与 mSA 存在相关的基线因素。此外,我们的第二个目的是了解 FEP 后首次自杀企图(SA)的时间上,单一和多次自杀企图者之间是否存在差异。
共评估了 65 名首发精神病患者。在 FEP 后两个不同的时间点记录 SAs 的发生情况。进行了单变量和多变量分析,以探讨 SA 与社会人口统计学和临床变量之间的关系。
多元线性回归显示,mSA 与症状严重程度增加(B=0.35;t=3.67;p<0.01)和一阶错误信念任务错误(B=0.48;t=2.11;p=0.04)有关。FEP 后首次 SA 的时间在多次和单次自杀企图者之间存在显著差异。
心理健康服务机构首次接触精神病症状时,心理理论损伤以及更严重的症状似乎是 mSA 的重要预测因素。另一方面,多次自杀企图者比单次自杀企图者更倾向于更早地进行首次 SA。这些结果可能有助于实施预防自杀的计划,但必须通过进一步的研究来证实。