Ryu Shunjin, Suwa Katsuhito, Kitagawa Takahiro, Aizawa Marie, Ushigome Takurou, Okamoto Tomoyoshi, Eto Ken, Yanaga Katsuhiko
Department of Surgery, The Jikei University School Daisan Hospital, Tokyo, Japan
Department of Surgery, The Jikei University School Daisan Hospital, Tokyo, Japan.
Anticancer Res. 2019 Jun;39(6):3009-3013. doi: 10.21873/anticanres.13433.
BACKGROUND/AIM: Indocyanine green (ICG) fluorescence technique is known to help visualize blood vessels. The efficacy of real-time fluorescence vessel navigation (FVN) using ICG for ligation of the inferior mesenteric vein (IMV) and left colic artery (LCA) during laparoscopic left colorectal cancer surgery was investigated.
Participants were 59 patients who underwent laparoscopic left colorectal cancer surgery from February 2017 to November 2018, and were divided into groups: i) with FVN (FVN+, n=21) and ii) without FVN (FVN-, n=38). Groups were compared for the time it took to ligate their IMV and LCA.
The results are expressed as median values. The time to ligate the IMV and LCA was significantly shorter for FVN+ (230 seconds; range 126-346) than for FVN- (417.5 seconds; range 137-1327) (p<0.001).
Real-time FVN using ICG shortened the times for IMV and LCA ligation. This was enabled by clear visualization of the direction of the bloodstream flow inside the vessels. This technique simplifies vessel ligation and safer laparoscopic surgery for left colorectal cancer.
背景/目的：吲哚菁绿（ICG）荧光技术有助于血管可视化。本研究旨在探讨在腹腔镜左半结肠癌手术中，使用ICG进行实时荧光血管导航（FVN）以结扎肠系膜下静脉（IMV）和左结肠动脉（LCA）的疗效。
选取2017年2月至2018年11月期间接受腹腔镜左半结肠癌手术的59例患者，分为两组：i）使用FVN组（FVN+，n=21）和ii）未使用FVN组（FVN-，n=38）。比较两组结扎IMV和LCA所需的时间。
结果以中位数表示。FVN+组结扎IMV和LCA的时间（230秒；范围126 - 346秒）显著短于FVN-组（417.5秒；范围137 - 1327秒）（p<0.001）。
使用ICG的实时FVN缩短了IMV和LCA的结扎时间。这是通过清晰可视化血管内血流方向实现的。该技术简化了血管结扎，使腹腔镜左半结肠癌手术更安全。
