Abel C, Glathe H
J Hyg Epidemiol Microbiol Immunol. 1978;22(3):375-81.
The authors examined 10 cell strains of different origin as to their effect on mice by means of antithymocytic (ATC) serum. In dependence on the strain used the tumors developed in different number and with different growth tendency. In control animals not treated by the ATC serum, small ganglions developed in some cases which, however, disappeared in 2--3 days. Both strains of diploide cells WI 38 and LEP and primary cultures of chicken fibroblast from embryos of SPF chickens did not develop any tumors. The antithymocytic serums from calfs were found to be less toxic for mice than the rabbit sera.
作者通过抗胸腺细胞（ATC）血清研究了10种不同来源的细胞株对小鼠的影响。根据所使用的细胞株不同，肿瘤的发生数量和生长趋势也有所不同。在未用ATC血清处理的对照动物中，有些情况下会出现小淋巴结，但在2 - 3天内就会消失。二倍体细胞株WI 38和LEP以及来自无特定病原体（SPF）鸡胚胎的鸡成纤维细胞原代培养物均未产生任何肿瘤。发现来自小牛的抗胸腺细胞血清对小鼠的毒性比兔血清小。
