Schober E, Scheibenreiter S, Frisch H
Universitäts-Kinderklinik Wien.
Monatsschr Kinderheilkd. 1987 Sep;135(9):660-2.
Basal and stimulated gonadotropin levels were evaluated in 8 children with galactosemia (2 boys, 6 girls). 5 girls demonstrated increased gonadotropin concentrations being in accordance with hypergonadotropic hypogonadism. It appears, that galactose and its metabolites-either dietary or by self-intoxication-exerts a toxic effect on the ovarian parenchyma, whereas the testis seems to be resistant to the damaging agent.
