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[Gonadotropin secretion in children with galactosemia].

作者信息

Schober E, Scheibenreiter S, Frisch H

机构信息

Universitäts-Kinderklinik Wien.

出版信息

Monatsschr Kinderheilkd. 1987 Sep;135(9):660-2.

PMID:3118201
Abstract

Basal and stimulated gonadotropin levels were evaluated in 8 children with galactosemia (2 boys, 6 girls). 5 girls demonstrated increased gonadotropin concentrations being in accordance with hypergonadotropic hypogonadism. It appears, that galactose and its metabolites-either dietary or by self-intoxication-exerts a toxic effect on the ovarian parenchyma, whereas the testis seems to be resistant to the damaging agent.

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