Division of Urology, Department of Surgery, College of Medicine, Penn State Health Milton S. Hershey Medical Center, The Pennsylvania State University, 500 University Drive, BMR Building c4830B, Hershey, PA, 17033-0850, USA.
College of Medicine, The Pennsylvania State University, Hershey, PA, USA.
Int Urol Nephrol. 2019 Aug;51(8):1291-1295. doi: 10.1007/s11255-019-02187-1. Epub 2019 Jun 10.
Adrenalectomy is performed to treat functional pathology and remove tumors of malignant concern. The National Surgical Quality Improvement Program (NSQIP) risk calculator predicts 30-day complications and length of stay following index surgical procedures. We assess whether this tool accurately predicts complications following adrenalectomy procedures at a tertiary care academic medical center.
A retrospective review was performed for all adrenalectomies at a single institution from 2004 to 2016. 197 patients underwent adrenalectomy without concurrent resections. Predicted risk for NSQIP complications was calculated for each patient. The mean predicted and observed risks (%) at 30 days across all patients within each category were determined, and these were compared with two-sided one-sample t tests.
Of 197 adrenalectomies, 180 were laparoscopic and 17 were open. For laparoscopic adrenalectomy, ten (5.5%) complications were observed including nine (5%) graded Clavien III or greater. All observed complication rates were significantly different than predicted (p values for all < 0.005). Mean observed length of stay was also significantly less than predicted (1.6 versus 2.1 days, p < 0.001). In the open adrenalectomy subgroup, there were no observed complications with observed mean length of stay equivalent to predicted (5.8 versus 5.3, p = 0.08) without a higher readmission rate (5.9 versus 6.0%).
Statistical differences were noted between the actual complication rates of adrenalectomy versus those predicted by the NSQIP calculator. Certain observed differences may not necessarily have clinical significance. Urology procedure-specific calculators may better refine predictions for sub-specialty procedures with future work requisite to determine performance across all practice settings.
肾上腺切除术用于治疗功能病变并切除恶性肿瘤。国家外科质量改进计划 (NSQIP) 风险计算器预测指数手术治疗后 30 天的并发症和住院时间。我们评估该工具是否能准确预测三级保健学术医疗中心的肾上腺切除术的并发症。
对 2004 年至 2016 年在一家机构进行的所有肾上腺切除术进行回顾性研究。197 例患者接受了无同期切除术的肾上腺切除术。为每位患者计算了 NSQIP 并发症的预测风险。确定了所有患者在每个类别的 30 天内的平均预测和观察风险(%),并通过双侧单样本 t 检验进行比较。
在 197 例肾上腺切除术患者中,180 例为腹腔镜手术,17 例为开放手术。对于腹腔镜肾上腺切除术,观察到十种(5.5%)并发症,包括 9 种(5%)分级为 Clavien III 或更高的并发症。所有观察到的并发症发生率均明显低于预测值(所有 p 值均<0.005)。观察到的平均住院时间也明显短于预测值(1.6 天比 2.1 天,p<0.001)。在开放肾上腺切除术亚组中,没有观察到并发症,观察到的平均住院时间与预测值相等(5.8 天比 5.3 天,p=0.08),且再入院率无升高(5.9 比 6.0%)。
实际的肾上腺切除术并发症率与 NSQIP 计算器预测的并发症率之间存在统计学差异。某些观察到的差异可能并不一定具有临床意义。未来需要进行进一步的工作,以确定所有实践环境中的表现,特定的泌尿科程序计算器可以更好地细化亚专业程序的预测。