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墨西哥 HPV 疫苗接种和筛查联合策略的可行性:FASTER-Tlalpan 研究经验。

Feasibility of a combined strategy of HPV vaccination and screening in Mexico: the FASTER-Tlalpan study experience.

机构信息

a Cátedra CONACYT- Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública , Cuernavaca , Morelos , México.

b Centro de Investigación en Políticas, Población y Salud, Facultad de Medicina, Universidad Autónoma de México , Ciudad de México , México.

出版信息

Hum Vaccin Immunother. 2019;15(7-8):1986-1994. doi: 10.1080/21645515.2019.1619401. Epub 2019 Jul 10.

Abstract

There has been a noticeable shift in discussions about cervical cancer, moving from prevention to elimination. Interventions such as FASTER, human papillomavirus (HPV) vaccination and HPV screening are innovative intervention strategies which can be utilized to begin a path to elimination. To explore the feasibility of the FASTER strategy, an evaluation was carried out in eight primary health-care centers within the Tlalpan Health-Jurisdiction of Mexico City between March 2017 and August 2018. A mixed methods approach was used to evaluate three components: infrastructure, patient acceptability, and health-care professionals' perceptions. This included checklists of requirements for the infrastructure rollout of FASTER and interviews with women and health-care professionals. Nearly all (93%) of the 3,474 women aged 25-45 years accepted HPV vaccination as part of a combined vaccination and screening program. The main reason for acceptance was prevention, while having doubts about the vaccine's benefits was the main reason for refusal. Most of the 24 health-care professionals had a positive opinion toward HPV vaccination and identified the need to increase dissemination, inform the population clearly and concisely and currently extend the age range for vaccination. The evaluation of eight primary health-care centers showed they had the necessary infrastructure for the development of a joint HPV prevention strategy, but many centers required improvements to become more efficient. Together these findings suggest that although HPV vaccine acceptance was high, there is the need to increase education and awareness among potential vaccine recipients and health-care professionals to implement the FASTER strategy.

摘要

关于宫颈癌的讨论已经发生了明显的转变,从预防转向消除。FASTER 等干预措施、人乳头瘤病毒(HPV)疫苗接种和 HPV 筛查是创新的干预策略,可以用来开辟消除宫颈癌的道路。为了探索 FASTER 策略的可行性,2017 年 3 月至 2018 年 8 月,在墨西哥城 Tlalpan 卫生管辖区的 8 个初级保健中心进行了评估。采用混合方法评估了三个方面:基础设施、患者可接受性和卫生保健专业人员的看法。这包括 FASTER 基础设施部署的检查表以及对妇女和卫生保健专业人员的访谈。年龄在 25-45 岁的 3474 名女性中,几乎所有人(93%)都接受了 HPV 疫苗接种,作为联合疫苗接种和筛查计划的一部分。接受疫苗接种的主要原因是预防,而对疫苗益处的怀疑是拒绝的主要原因。24 名卫生保健专业人员中的大多数对 HPV 疫苗接种持积极态度,并认为有必要增加宣传,明确、简洁地告知民众,并扩大目前的疫苗接种年龄范围。对 8 个初级保健中心的评估表明,它们具备开展联合 HPV 预防策略的必要基础设施,但许多中心需要改进以提高效率。这些发现表明,尽管 HPV 疫苗接种的接受率很高,但需要增加潜在疫苗接种者和卫生保健专业人员的教育和认识,以实施 FASTER 策略。

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